CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-018629
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Thioredoxin-like protein 1 
Protein Synonyms/Alias
 Thioredoxin-related protein 
Gene Name
 Txnl1 
Gene Synonyms/Alias
 Trp 
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
102DAVGLEEKIKQHLENubiquitination[1]
181PVKLYSMKFQGPDNGubiquitination[1]
Reference
 [1] Synaptic protein ubiquitination in rat brain revealed by antibody-based ubiquitome analysis.
 Na CH, Jones DR, Yang Y, Wang X, Xu Y, Peng J.
 J Proteome Res. 2012 Sep 7;11(9):4722-32. [PMID: 22871113] 
Functional Description
 Active thioredoxin with a redox potential of about -250 mV (By similarity). 
Sequence Annotation
 DOMAIN 2 109 Thioredoxin.
 DOMAIN 115 285 PITH.
 MOD_RES 113 113 Phosphoserine (By similarity).
 DISULFID 34 37 Redox-active (By similarity).  
Keyword
 Complete proteome; Cytoplasm; Direct protein sequencing; Disulfide bond; Electron transport; Nucleus; Phosphoprotein; Proteasome; Redox-active center; Reference proteome; Transport. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 289 AA 
Protein Sequence
MVGVKPVGSD PDFQPELSGA GSRLAVVKFT MRGCGPCLRI APAFSSMSNK YPQAVFLEVD 60
VHQCQGTAAT NNISATPTFL FFRNKVRIDQ YQGADAVGLE EKIKQHLEND PGSNEDTDIP 120
KGYMDLMPFI NKAGCECLNE SDEHGFDNCL RKDLSFLESD CDEQLLITVA FNQPVKLYSM 180
KFQGPDNGQG PKYVKIFINL PRSMDFEEAE RSEPTQALEL TEDDIKEDGI VPLRYVKFQN 240
VNSVTLFVQS NQGEEETTRI SYFTFIGTPV QATNMNDFKR VVGKKGESH 289 
Gene Ontology
 GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
 GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
 GO:0000502; C:proteasome complex; IEA:UniProtKB-KW.
 GO:0009055; F:electron carrier activity; IEA:InterPro.
 GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
 GO:0045454; P:cell redox homeostasis; IEA:InterPro.
 GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.
 GO:0006662; P:glycerol ether metabolic process; IEA:InterPro. 
Interpro
 IPR008979; Galactose-bd-like.
 IPR010400; PITH_dom.
 IPR005746; Thioredoxin.
 IPR012336; Thioredoxin-like_fold.
 IPR017937; Thioredoxin_CS.
 IPR013766; Thioredoxin_domain. 
Pfam
 PF06201; PITH
 PF00085; Thioredoxin 
SMART
  
PROSITE
 PS51532; PITH
 PS00194; THIOREDOXIN_1
 PS51352; THIOREDOXIN_2 
PRINTS