CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-038494
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Zinc finger ZZ-type and EF-hand domain-containing protein 1 
Protein Synonyms/Alias
  
Gene Name
 Zzef1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
220TMRSSVLKESLDQLVubiquitination[1]
2079VFAECSQKRILGLLAubiquitination[1]
2254RAVIVDVKTRKRKTVubiquitination[1]
2324LALKGLYKTLKAHGFacetylation[2]
2454IYELQMKKTDSFFLEubiquitination[1]
2464SFFLEVQKRFDGDELubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023]
 [2] Quantification of mitochondrial acetylation dynamics highlights prominent sites of metabolic regulation.
 Still AJ, Floyd BJ, Hebert AS, Bingman CA, Carson JJ, Gunderson DR, Dolan BK, Grimsrud PA, Dittenhafer-Reed KE, Stapleton DS, Keller MP, Westphall MS, Denu JM, Attie AD, Coon JJ, Pagliarini DJ.
 J Biol Chem. 2013 Jul 17;. [PMID: 23864654] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 2924 AA 
Protein Sequence
MGNAPSNSSE DEAAAAGGEG WSPHQDWAAD SGTTPGPGPA AAVLPSAAAL LEPARLREAA 60
AALRPAPPCE SLVSRHHGAL LRWLEERLGR GEESVTLEQF RELLEARGAG CSGEQFEEAF 120
AQFDAEGDGT VDAENMLEAL KNSSGANLQG ELSHVIRQLQ ACSLVPGFID IFSESKEGLG 180
IHSSMILRFL HRNRISSMVI PYPMLDHCNN MCTMRSSVLK ESLDQLVQKE KESPGDLARS 240
PEMDKLKSVT KCYAYIETSS NPADIYRMTN GETSSYWQSD GSARSHWIRL KMKPDVVLRH 300
LSIAVAATDQ SYMPQQVTVA VGRSASDLQE VRDVHIPSNV TGYVTLLENA NISQLYVQIN 360
IKRCLSDGCD TRIHGLRAVG FQRVKKSGVS VSDASAIWYW SLLTSLVTAS METNPAFVQT 420
VLHNTQKALQ HMPPLSLSPG STDFSTFLSP NVLEEVDSFL IRITSCCSTP EVELTLLAFA 480
LARGSIAKVM SSLCTITDHL DTQYDASSLI SSMASVRQNL LLKYGKPLQL TLQACDVKGK 540
EDKSGPENLL VEPWTRDGFL TETGKTRAST IFSTGSDSAF QVTQIRIMVR RGGIGAQCGL 600
VFAYNSPSNK FHAEEHFKRF EKYDKWKLQE LRQFVKSRIG CSSDDLGEDD PIGWFELEEE 660
WDEADVKLQQ CRVAKFLMVK FLCTRQESAE RLGVQGLSIS GYLRPARAEA EQSILYAHCR 720
RDTENIHGAT LLLRTLQFIQ QLSHDLMQQK ESGLKHKSFL DFAGLDLQIF WKFYSKLKQN 780
RREECICAQT LLLKLLQSCF SVLQGDPQAA SEEEKPTAQR SEGIQAAKEL YTHLCNVVDK 840
PNGNSMPMEI LKQEVRNTLL NGAAIFFPDR QTRRSQLFTM MKSVTEHERK QSLQLTFHSL 900
CTYFSDKDPG GLLLLPEKSD LATMNTSEVL AVMNTLLSVA ARECELLMLN RSHGAVGSVL 960
FSLFWSVQGS LLSWCFLQLK STDAAAKELA MDLIEKYVGQ FLASMRVILE SLLSQYSGKT 1020
IVEKLCNSVF SMAARQLVIF LLDFCTLDVS HCTLLREFST LTELLKKLCS DPEGGLSKLD 1080
VETWQQEQPV VLHTWTKEST HNYENNCHEV SVFISPGATY FEVEFDERCE TEKRYDYLEF 1140
TDSRGGKTRY DTKVGTYKWP KKVTFKDGPR LQFLFHSDSS NNEWGYKFTV TAYGLPDVAV 1200
SWGLDLQLLV SRLMGRLASQ CMALKSVHQL GSNMAVSQAK LTSVLNSPLW KPVFRHQICP 1260
ELELEASWPT HPHKDGKEVK NIPDDPCRHF LLDFAQSEPA QNFCGPYSEL FKGFIQACRK 1320
QAPKTDIVAG STIDQAVNAT FAALVYRTPD LYEKLQKYVN SGGKIALTEE FSQVYSLADG 1380
IRIWMLEMKQ KSLLSLGNDS EEKRGLEAAE VNPESLAKEC IQKSLLLLKF LPMSKSSKEN 1440
CDKLETVDET DHLQPLDRRQ RTSSVVEEHF QGSASPTEAA TPAAGDRSPA LEIQPKLLPS 1500
SGPCVAEVST AEEPSPPSTP TRRPPFTRGR LRLLSFRSME ETRPVPTVKE KYPVLKDVMD 1560
FIKDQSLSHE SVVKVLSLRK AQGQSILEVL RIIQYCTESL GQPHCFHPPY ILFLLELLTC 1620
QKDFTNYFGH LEGCGADLHR EIRDTYYQLV LFLVKAIKRF SSINDRSLLP ALSCVQTALL 1680
HLLDMGWEPS DLAFFVDIQL PDLLMNMSQE NISVHDSVIS QWSEEDELAD AKQNSEWMDE 1740
CQDGMFEAWY EKIAQEDPEK QRKMHMFIAR YCDLLNVDIS CDGCDEIAPW HRYRCLQCSD 1800
MDLCKTCFLG GVKPEGHGDD HEMVNMEFTC DHCQGLIIGR RMNCNVCDDF DLCYGCYTAK 1860
KYSYGHLPTH SITAHPMVTI RISDRQRLIQ PYIHNYSWLL FAALALYSAH LTSTEQVDGE 1920
QLDPQARTNA ATLRSQCMQL VGDCLMKAHQ GKGLKALALL GVLPDGDSTS ENQALPVTVS 1980
FQASEEQADA GLLVPCNGKR AADTEVRPLD YKQKKKAGED LSIVKDPSCQ TQVSDAPASA 2040
HVPPGLPDAE HPEVSAQVLV EEKAITPNPE QVFAECSQKR ILGLLAAMLP PIKSGPTVPL 2100
IDLEHVLPLM FQVVISNAGH LNETYHLTLG LLGQLIIRLQ PAEVDAAVMK VLSAKHNLRV 2160
GLDWACSMAE ILRSLNNAPL WRDVIATFTD HCIKQLPFQL KHTNIFTLLV LVGFPQVLCV 2220
GTRCVYMDNA NEPHNVIILK HFTEKNRAVI VDVKTRKRKT VKDYQLVQKG GGQECGTSQS 2280
QLSQYSQHFA FIASHLLQTS MDSHCPEAVE ATWVLSLALK GLYKTLKAHG FEETHATFLQ 2340
TDLLKLLVKK CSKGTGFSKT WLLRDLEILS IMLYSSKKEI NTLAEHGDLE LDERGDQEEE 2400
LDRPVSSPGE AEQKKLDPLE NLDEPTRICF LMAHDALNAP LHILRAIYEL QMKKTDSFFL 2460
EVQKRFDGDE LTTDERIRSL AQRWQPSRSL RLEEQSAKAV DTDMIILPCL SRPARSDQAT 2520
PESNPVTQKL ISSTESELQQ SYAKQRRSKS AALLHKELNC KSKRAIRDYL FRVNEATSVL 2580
YARHVLASLL AEWPGHVPVS EDILELSGPA HMTYILDMFM QLEEKHQWEK ILQKVLQGCR 2640
ENMLGTMALA ACQFMEEPGM EVQVRESKHP YNNNTSFEDK VHIPGAIYLS IKFDPQCNTE 2700
EGCDELAMSS SSDFQQDRHN FSGSQQKWKD FELPGDTLYY RFTSDMSNTE WGYRFTVTAG 2760
HLGRFQTGFE ILKQMLSEER VVPHLALGKI WEWLVGVACR QTGHQRLKAI HLLLRIVQCC 2820
SHSDLCDLGL LKPLWQLFTH MEYGLFEDVT QPGILLPLHR ALTELFFVTE NRAQELGLLQ 2880
EYLLALTTED HLLRCAAQAL QNIAAISLAI NYPNKATRLW NVEC 2924 
Gene Ontology
 GO:0005509; F:calcium ion binding; IEA:InterPro.
 GO:0008270; F:zinc ion binding; IEA:InterPro. 
Interpro
 IPR004939; APC_su10/DOC_dom.
 IPR000859; CUB_dom.
 IPR011992; EF-hand-like_dom.
 IPR002048; EF_hand_dom.
 IPR008979; Galactose-bd-like.
 IPR000433; Znf_ZZ. 
Pfam
 PF03256; APC10
 PF00569; ZZ 
SMART
 SM00291; ZnF_ZZ 
PROSITE
 PS51284; DOC
 PS50222; EF_HAND_2
 PS01357; ZF_ZZ_1
 PS50135; ZF_ZZ_2 
PRINTS