| Tag | Content |
|---|
| CPLM ID | CPLM-014560 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Zinc finger protein with KRAB and SCAN domains 2 |
Protein Synonyms/Alias | Zinc finger protein 694 |
Gene Name | ZKSCAN2 |
Gene Synonyms/Alias | ZNF694 |
Created Date | July 27, 2013 |
Organism | Homo sapiens (Human) |
NCBI Taxa ID | 9606 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 894 | YKCVDCEKSFNNCTR | ubiquitination | [1] |
|
Reference | [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments. Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA. Mol Cell Proteomics. 2013 Mar;12(3):825-31. [ PMID: 23266961] |
Functional Description | May be involved in transcriptional regulation. |
Sequence Annotation | DOMAIN 45 127 SCAN box.
DOMAIN 229 300 KRAB.
ZN_FING 775 797 C2H2-type 1.
ZN_FING 803 825 C2H2-type 2.
ZN_FING 831 853 C2H2-type 3.
ZN_FING 859 881 C2H2-type 4.
ZN_FING 887 909 C2H2-type 5.
ZN_FING 915 937 C2H2-type 6.
MOD_RES 591 591 Phosphoserine.
MOD_RES 600 600 Phosphoserine. |
Keyword | Alternative splicing; Complete proteome; DNA-binding; Metal-binding; Nucleus; Phosphoprotein; Polymorphism; Reference proteome; Repeat; Transcription; Transcription regulation; Zinc; Zinc-finger. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 967 AA |
Protein Sequence | MAVALDSQID APLEVEGCLI MKVEKDPEWA SEPILEGSDS SETFRKCFRQ FCYEDVTGPH 60
EAFSKLWELC CRWLKPEMRS KEQILELLVI EQFLTILPEK IQAWAQKQCP QSGEEAVALV 120
VHLEKETGRL RQQVSSPVHR EKHSPLGAAW EVADFQPEQV ETQPRAVSRE EPGSLHSGHQ 180
EQLNRKRERR PLPKNARPSP WVPALADEWN TLDQEVTTTR LPAGSQEPVK DVHVARGFSY 240
RKSVHQIPAQ RDLYRDFRKE NVGNVVSLGS AVSTSNKITR LEQRKEPWTL GLHSSNKRSI 300
LRSNYVKEKS VHAIQVPARS AGKTWREQQQ WGLEDEKIAG VHWSYEETKT FLAILKESRF 360
YETLQACPRN SQVYGAVAEW LRECGFLRTP EQCRTKFKSL QKSYRKVRNG HMLEPCAFFE 420
DMDALLNPAA RAPSTDKPKE MIPVPRLKRI AISAKEHISL VEEEEAAEDS DDDEIGIEFI 480
RKSEIHGAPV LFQNLSGVHW GYEETKTFLD ILRETRFYEA LQACHRKSKL YGAVAEQLRE 540
CGFLRTPEQC RTKFKSLQKS YRKVKNGHVL ESCAFYKEMD ALINSRASAP SPSTPEEVPS 600
PSRQERGGIE VEPQEPTGWE PEETSQEAVI EDSCSERMSE EEIVQEPEFQ GPPGLLQSPN 660
DFEIGSSIKE DPTQIVYKDM EQHRALIEKS KRVVSQSTDP SKYRKRECIS GRQWENLQGI 720
RQGKPMSQPR DLGKAVVHQR PFVGKRPYRL LKYGESFGRS TRLMCRMTHH KENPYKCGVC 780
GKCFGRSRSL IRHQRIHTGE KPFKCLDCGK SFNDSSNFGA HQRIHTGEKP YRCGECGKCF 840
SQSSSLIIHQ RTHTGEKPYQ CGECGKSFTN SSHFSAHRRV HTGENPYKCV DCEKSFNNCT 900
RFREHRRIHT GEKPYGCAQC GKRFSKSSVL TKHREVHVRE KPLPHPPSLY CPENPHKGKT 960
DEFRKTF 967 |
Gene Ontology | GO:0005634; C:nucleus; IBA:RefGenome. GO:0003682; F:chromatin binding; IEA:InterPro. GO:0003677; F:DNA binding; IEA:UniProtKB-KW. GO:0000981; F:sequence-specific DNA binding RNA polymerase II transcription factor activity; IBA:RefGenome. GO:0008270; F:zinc ion binding; IEA:InterPro. GO:0016032; P:viral reproduction; IEA:InterPro. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |