UniProt Accession

 MOT10_HUMAN; Q8TF71; B3KWY0; Q6ZMG0; Q8WVI5 

Genbank Protein ID

 AB057445; AK126183; AK172789; AL360227; CH471051; BC017968; BC066985 

Genbank Nucleotide ID

 BAB84670.1; BAG54292.1; BAD18768.1; CAH73732.1; EAW48298.1; AAH17968.1; AAH66985.1 

Protein Name

 Monocarboxylate transporter 10 

Protein Synonyms/Alias

 MCT 10; Aromatic amino acid transporter 1; Solute carrier family 16 member 10; T-type amino acid transporter 1 

Gene Name

 SLC16A10 

Gene Synonyms/Alias

 MCT10; TAT1 

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
508	SSSSGMFKKESDSII	ubiquitination	[1, 2, 3]

Reference

 [1] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473]
 [2] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [3] hCKSAAP_UbSite: improved prediction of human ubiquitination sites by exploiting amino acid pattern and properties.
 Chen Z, Zhou Y, Song J, Zhang Z.
 Biochim Biophys Acta. 2013 Aug;1834(8):1461-7. [PMID: 23603789] 

Functional Description

 Sodium-independent transporter that mediates the update of aromatic acid. Can function as a net efflux pathway for aromatic amino acids in the basosolateral epithelial cells (By similarity). 

Sequence Annotation

 MOD_RES 269 269 Phosphoserine (By similarity).
 MOD_RES 498 498 Phosphoserine.
 MOD_RES 504 504 Phosphoserine (By similarity).  

Keyword

 Cell membrane; Complete proteome; Membrane; Phosphoprotein; Polymorphism; Reference proteome; Transmembrane; Transmembrane helix; Transport. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 515 AA 

Protein Sequence

Gene Ontology

 GO:0016323; C:basolateral plasma membrane; TAS:HGNC.
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0015801; P:aromatic amino acid transport; TAS:HGNC.
 GO:0055085; P:transmembrane transport; TAS:Reactome. 

Interpro

 IPR011701; MFS.
 IPR020846; MFS_dom.
 IPR016196; MFS_dom_general_subst_transpt. 

Pfam

 PF07690; MFS_1 

SMART

  

PROSITE

 PS50850; MFS 

PRINTS