CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-043336
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 M-phase phosphoprotein 6 
Protein Synonyms/Alias
  
Gene Name
 MPHOSPH6 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
68GFNPEVEKLMLQMNAubiquitination[1, 2, 3]
78LQMNAKHKAEEVEDEubiquitination[2]
109TLVGTIGKKFARKRDubiquitination[1]
110LVGTIGKKFARKRDHubiquitination[2]
114IGKKFARKRDHANYEubiquitination[2]
132NGDITPIKAKKMFLKubiquitination[1]
135ITPIKAKKMFLKPQDubiquitination[2]
139KAKKMFLKPQD****acetylation[4]
139KAKKMFLKPQD****ubiquitination[2]
Reference
 [1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [2] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [3] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302]
 [4] Proteomic investigations reveal a role for RNA processing factor THRAP3 in the DNA damage response.
 Beli P, Lukashchuk N, Wagner SA, Weinert BT, Olsen JV, Baskcomb L, Mann M, Jackson SP, Choudhary C.
 Mol Cell. 2012 Apr 27;46(2):212-25. [PMID: 22424773
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 142 AA 
Protein Sequence
MQRGLDSETK KQLEEEEKKI ISEEHWYLDL PELKEKESFI IEEQSFLLCE DLLYGRMSFR 60
GFNPEVEKLM LQMNAKHKAE EVEDETVELD VSDEEMARRY ETLVGTIGKK FARKRDHANY 120
EEDENGDITP IKAKKMFLKP QD 142 
Gene Ontology
  
Interpro
 IPR019324; MPP6. 
Pfam
 PF10175; MPP6 
SMART
  
PROSITE
  
PRINTS