CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-037458
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 5'-AMP-activated protein kinase subunit gamma-2 
Protein Synonyms/Alias
  
Gene Name
 PRKAG2 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
351KVVDIYSKFDVINLAubiquitination[1, 2, 3, 4]
361VINLAAEKTYNNLDIubiquitination[4]
Reference
 [1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [2] Global identification of modular cullin-RING ligase substrates.
 Emanuele MJ, Elia AE, Xu Q, Thoma CR, Izhar L, Leng Y, Guo A, Chen YN, Rush J, Hsu PW, Yen HC, Elledge SJ.
 Cell. 2011 Oct 14;147(2):459-74. [PMID: 21963094]
 [3] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [4] Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization.
 Sarraf SA, Raman M, Guarani-Pereira V, Sowa ME, Huttlin EL, Gygi SP, Harper JW.
 Nature. 2013 Apr 18;496(7445):372-6. [PMID: 23503661
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 445 AA 
Protein Sequence
MKRFGSLRSN KKHKDQNRST ERRQSEPHGL FASGLSSSPS TPTQVTKQHT FPLESYKHEP 60
ERLENRIYAS SSPPDTGQRF CPSSFQSPTR PPLASPTHYA PSKAAALAAA LGPAEAGMLE 120
KLEFEDEAVE DSESGVYMRF MRSHKCYDIV PTSSKLVVFD TTLQVKKAFF ALVANGVRAA 180
PLWESKKQSF VGMLTITDFI NILHRYYKSP MVQIYELEEH KIETWRELYL QETFKPLVNI 240
SPDASLFDAV YSLIKNKIHR LPVIDPISGN ALYILTHKRI LKFLQLFMSD MPKPAFMKQN 300
LDELGIGTYH NIAFIHPDTP IIKALNIFVE RRISALPVVD ESGKVVDIYS KFDVINLAAE 360
KTYNNLDITV TQALQHRSQY FEGVVKCNKL EILETIVDRI VRAEVHRLVV VNEADSIVGI 420
ISLSDILQAL ILTPAGAKQK ETETE 445 
Gene Ontology
  
Interpro
 IPR000644; Cysta_beta_synth_core. 
Pfam
 PF00571; CBS 
SMART
 SM00116; CBS 
PROSITE
 PS51371; CBS 
PRINTS