CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-011726
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Citrate synthase 1 
Protein Synonyms/Alias
  
Gene Name
 gltA2 
Gene Synonyms/Alias
 gltA; Rv0896; MT0920; MTCY31.24 
Created Date
 July 27, 2013 
Organism
 Mycobacterium tuberculosis 
NCBI Taxa ID
 1773 
Lysine Modification
Position
Peptide
Type
References
328IVKEQADKILAKLGGpupylation[1]
Reference
 [1] Prokaryotic ubiquitin-like protein (Pup) proteome of Mycobacterium tuberculosis [corrected] .
 Festa RA, McAllister F, Pearce MJ, Mintseris J, Burns KE, Gygi SP, Darwin KH.
 PLoS One. 2010 Jan 6;5(1):e8589. [PMID: 20066036
Functional Description
  
Sequence Annotation
 ACT_SITE 309 309 By similarity.
 ACT_SITE 366 366 By similarity.
 CROSSLNK 328 328 Isoglutamyl lysine isopeptide (Lys-Gln)  
Keyword
 Allosteric enzyme; Complete proteome; Isopeptide bond; Reference proteome; Transferase; Tricarboxylic acid cycle; Ubl conjugation. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 431 AA 
Protein Sequence
MADTDDTATL RYPGGEIDLQ IVHATEGADG IALGPLLAKT GHTTFDVGFA NTAAAKSSIT 60
YIDGDAGILR YRGYPIDQLA EKSTFIEVCY LLIYGELPDT DQLAQFTGRI QRHTMLHEDL 120
KRFFDGFPRN AHPMPVLSSV VNALSAYYQD ALDPMDNGQV ELSTIRLLAK LPTIAAYAYK 180
KSVGQPFLYP DNSLTLVENF LRLTFGFPAE PYQADPEVVR ALDMLFILHA DHEQNCSTST 240
VRLVGSSRAN LFTSISGGIN ALWGPLHGGA NQAVLEMLEG IRDSGDDVSE FVRKVKNREA 300
GVKLMGFGHR VYKNYDPRAR IVKEQADKIL AKLGGDDSLL GIAKELEEAA LTDDYFIERK 360
LYPNVDFYTG LIYRALGFPT RMFTVLFALG RLPGWIAHWR EMHDEGDSKI GRPRQIYTGY 420
TERDYVTIDA R 431 
Gene Ontology
 GO:0005829; C:cytosol; IDA:MTBBASE.
 GO:0005886; C:plasma membrane; IDA:MTBBASE.
 GO:0004108; F:citrate (Si)-synthase activity; IEA:EC.
 GO:0044262; P:cellular carbohydrate metabolic process; IEA:InterPro.
 GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-UniPathway. 
Interpro
 IPR016142; Citrate_synth-like_lrg_a-sub.
 IPR016143; Citrate_synth-like_sm_a-sub.
 IPR002020; Citrate_synthase-like.
 IPR016141; Citrate_synthase-like_core.
 IPR019810; Citrate_synthase_AS.
 IPR024176; Citrate_synthase_bac-typ.
 IPR010953; Citrate_synthase_typ-II. 
Pfam
 PF00285; Citrate_synt 
SMART
  
PROSITE
 PS00480; CITRATE_SYNTHASE 
PRINTS
 PR00143; CITRTSNTHASE.