CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-041942
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Histone-lysine N-methyltransferase Smyd1 
Protein Synonyms/Alias
  
Gene Name
 Smyd1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
269KPSQEVVKEMIQFSKubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Metal-binding; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 456 AA 
Protein Sequence
MKNGEACGGW QSLINFVCHT CFKRQEKLHR CGQCKFAHYC DRTCQKDAWL NHKNECAAIK 60
KYGKVPNENI RLAARIMWRV EREGTGLTEG CLVSVDDLQN HVEHFGEEEQ KELRVDVDTF 120
LQYWPPQSQQ FSMQYISHIF GVINCNGFTL SDQRGLQAVG VGIFPNLGLV NHDCWPNCTV 180
IFNNGNHEAV KSMFHTQMRI ELRALGKISE GEELTVSYID FLHLSEERRR QLKKQYYFDC 240
SCEHCQKGLK DDLFLAAKED PKPSQEVVKE MIQFSKDTLE KIDKARSEGL YHEVVKLCRE 300
CLEKQEPVFA DTNLYVLRLL SIASEVLSYL QAYEEASHYA RRMVDGYMKL YHHNNAQLGM 360
AVMRAGLTNW HAGHIEVGHG MICKAYAILL VTHGPSHPIT KDLEAMRMQT EMELRMFRQN 420
EFMYHKMREA ALNNQPMQVM AEPSNEPAPA LFHKKQ 456 
Gene Ontology
 GO:0005737; C:cytoplasm; IDA:MGI.
 GO:0005634; C:nucleus; IDA:MGI.
 GO:0003714; F:transcription corepressor activity; IDA:MGI.
 GO:0008270; F:zinc ion binding; IEA:InterPro.
 GO:0006338; P:chromatin remodeling; IPI:MGI.
 GO:0007507; P:heart development; IMP:MGI.
 GO:0045892; P:negative regulation of transcription, DNA-dependent; IDA:MGI.
 GO:0035914; P:skeletal muscle cell differentiation; IMP:MGI. 
Interpro
 IPR001214; SET_dom.
 IPR002893; Znf_MYND. 
Pfam
 PF00856; SET
 PF01753; zf-MYND 
SMART
 SM00317; SET 
PROSITE
 PS50280; SET
 PS01360; ZF_MYND_1
 PS50865; ZF_MYND_2 
PRINTS