UniProt Accession

 F6YPR4_MOUSE; F6YPR4 

Genbank Protein ID

 AC119211; AC162614 

Genbank Nucleotide ID

  

Protein Name

 Tyrosine-protein kinase receptor UFO 

Protein Synonyms/Alias

  

Gene Name

 Axl 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Mus musculus (Mouse) 

NCBI Taxa ID

 10090 

Lysine Modification

Position	Peptide	Type	References
141	LGISEELKEKLRDVM	ubiquitination	[1]
158	RHKVALGKTLGEGEF	ubiquitination	[1]

Reference

 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 188 AA 

Protein Sequence

Gene Ontology

 GO:0005524; F:ATP binding; IEA:InterPro.
 GO:0004672; F:protein kinase activity; IEA:InterPro.
 GO:0043277; P:apoptotic cell clearance; IMP:MGI.
 GO:0001974; P:blood vessel remodeling; IMP:MGI.
 GO:0031668; P:cellular response to extracellular stimulus; IDA:MGI.
 GO:0007167; P:enzyme linked receptor protein signaling pathway; IGI:MGI.
 GO:0034101; P:erythrocyte homeostasis; IMP:MGI.
 GO:0021885; P:forebrain cell migration; IGI:MGI.
 GO:0006954; P:inflammatory response; IMP:MGI.
 GO:0001779; P:natural killer cell differentiation; IGI:MGI.
 GO:0051250; P:negative regulation of lymphocyte activation; IGI:MGI.
 GO:0043524; P:negative regulation of neuron apoptotic process; IMP:MGI.
 GO:0032720; P:negative regulation of tumor necrosis factor production; IGI:MGI.
 GO:0001764; P:neuron migration; IMP:MGI.
 GO:0042698; P:ovulation cycle; IGI:MGI.
 GO:0030168; P:platelet activation; IMP:MGI.
 GO:0043491; P:protein kinase B signaling cascade; IMP:MGI.
 GO:0032940; P:secretion by cell; IMP:MGI.
 GO:0007283; P:spermatogenesis; IGI:MGI.
 GO:0034446; P:substrate adhesion-dependent cell spreading; IMP:MGI.
 GO:0060068; P:vagina development; IGI:MGI. 

Interpro

 IPR003961; Fibronectin_type3.
 IPR013783; Ig-like_fold.
 IPR011009; Kinase-like_dom.
 IPR017441; Protein_kinase_ATP_BS.
 IPR001245; Ser-Thr/Tyr_kinase_cat_dom. 

Pfam

 PF07714; Pkinase_Tyr 

SMART

  

PROSITE

 PS00107; PROTEIN_KINASE_ATP 

PRINTS