CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-033259
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Metaxin-2 
Protein Synonyms/Alias
  
Gene Name
 MTX2 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
93GPIVQFVKAKGHSLSubiquitination[1]
95IVQFVKAKGHSLSDGubiquitination[1, 2, 3]
108DGLEEVQKAEMKAYMubiquitination[2, 3]
154KAIGWGKKTLDQVLEubiquitination[3]
214DELSEKVKNYSNLLAubiquitination[3]
Reference
 [1] Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization.
 Sarraf SA, Raman M, Guarani-Pereira V, Sowa ME, Huttlin EL, Gygi SP, Harper JW.
 Nature. 2013 Apr 18;496(7445):372-6. [PMID: 23503661]
 [2] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [3] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 229 AA 
Protein Sequence
MSLVAEAFVS QIAAAEPWPE NATLYQQLKG EQILLSDNAA SLAVQAFLQM CNLPIKVVCR 60
ANAEYMSPSG KVPFIHVGNQ VVSELGPIVQ FVKAKGHSLS DGLEEVQKAE MKAYMELVNN 120
MLLTAELYLQ WCDEATVGEW EVKRKMKAIG WGKKTLDQVL EDVDQCCQAL SQRLGTQPYF 180
FNKQPTELDA LVFGHLYTIL TTQLTNDELS EKVKNYSNLL AFCRRIEQH 229 
Gene Ontology
 GO:0005741; C:mitochondrial outer membrane; IEA:InterPro.
 GO:0006626; P:protein targeting to mitochondrion; IEA:InterPro. 
Interpro
 IPR010987; Glutathione-S-Trfase_C-like.
 IPR017933; Glutathione_S_Trfase/Cl_chnl_C.
 IPR019564; Sam37/metaxin. 
Pfam
 PF10568; Tom37 
SMART
  
PROSITE
 PS50405; GST_CTER 
PRINTS