CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-029651
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 TBC1 domain family member 22A 
Protein Synonyms/Alias
 TBC1 domain family, member 22A, isoform CRA_c; cDNA FLJ45751 fis, clone LYMPB2002344, highly similar to TBC1 domain family member 22A 
Gene Name
 TBC1D22A 
Gene Synonyms/Alias
 hCG_1734981 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
155ASRLDKFKQLLAGPNubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 470 AA 
Protein Sequence
MPTTPVKAKR VSTFQEFESN TSDAWDAGED DDELLAMAAE SLNSEVVMET ANRVLRNHSQ 60
RQGRPTLQEG PGLQQKPRPE AEPPSPPSGD LRLVKSVSES HTSCPAESAS DAAPLQRSQS 120
LPHSATVTLG GTSDPSTLSS SALSEREASR LDKFKQLLAG PNTDLEELRR LSWSGIPKPV 180
RPMTWKLLSG YLPANVDRRP ATLQRKQKEY FAFIEHYYDS RNDEVHQDTY RQIHIDIPRM 240
SPEALILQPK VTEIFERILF IWAIRHPASG YVQGINDLVT PFFVVFICEY IEAEEVDTVD 300
VSGVPAEVLC NIEADTYWCM SKLLDGIQDN YTFAQPGIQM KVKMLEELVS RIDEQVHRHL 360
DQHEVRYLQF AFRWMNNLLM REVPLRCTIR LWDTYQSEPD GFSHFHLYVC AAFLVRWRKE 420
ILEEKDFQEL LLFLQNLPTA HWDDEDISLL LAEAYRLKFA FADAPNHYKK 470 
Gene Ontology
 GO:0005622; C:intracellular; IEA:InterPro.
 GO:0005097; F:Rab GTPase activator activity; IEA:InterPro.
 GO:0032851; P:positive regulation of Rab GTPase activity; IEA:GOC. 
Interpro
 IPR000195; Rab-GTPase-TBC_dom. 
Pfam
 PF00566; RabGAP-TBC 
SMART
 SM00164; TBC 
PROSITE
 PS50086; TBC_RABGAP 
PRINTS