CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-024528
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Ankyrin repeat domain-containing protein 36A 
Protein Synonyms/Alias
  
Gene Name
 ANKRD36 
Gene Synonyms/Alias
 ANKRD36A; KIAA1641; UNQ2430/PRO499 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
29AFPQYPIKPYHLKRIubiquitination[1]
60LTYYDANKRDRKERTubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961
Functional Description
  
Sequence Annotation
 REPEAT 31 60 ANK 1.
 REPEAT 64 93 ANK 2.
 REPEAT 97 126 ANK 3.
 REPEAT 130 159 ANK 4.
 REPEAT 163 192 ANK 5.
 REPEAT 196 225 ANK 6.  
Keyword
 Alternative splicing; ANK repeat; Coiled coil; Complete proteome; Reference proteome; Repeat. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1941 AA 
Protein Sequence
MEDGKRERWP TLMERLCSDG FAFPQYPIKP YHLKRIHRAV LHGNLEKLKY LLLTYYDANK 60
RDRKERTALH LACATGQPEM VHLLVSRRCE LNLCDREDRT PLIKAVQLRQ EACATLLLQN 120
GANPNITDFF GRTALHYAVY NEDTSMIEKL LSHGTNIEEC SKCEYQPLLF AVSRRKVKMV 180
EFLLKKKANV NAIDYLGRSA LIHAVTLGEK DIVILLLQHN IDVLSRDAFR KIAGDYAIEA 240
KNRVIFDLIY EYERKRYEDL PINSNPVSSQ KQPALKATSG KEDSISNIAT EIKDGQKSGT 300
VSSQKQPALK DTSDKDDSVS NTATEIKDEQ KSGTVLPAVE QCLNRSLYRP DAVAQPVTEN 360
EFSLESEIIS KLYIPKRKII SPRSIKDVLP PVEEAVDRCL YLLDRFAQPV TKDKFALESE 420
NISEPYFTNR RTISQQSAEN LDAACGIDKT ENGNMFEDQN VDKEGKALPA TGQKANVSPE 480
QPPLFTHTVK DRDHISTRFL GGMDSLTSSE ESSERPPLST LTLKEADPSS KAAMRRKDSP 540
PPGKVSSQKQ PAEKATSDDK DSVSNIATEI KEGPISGTVS SQKQPAEKAT SDEKDSVSNI 600
ATEIKKGQQS GTVSPQKQSA WKVIFKKKVS LLNIATRIMG GGKSGTVSSQ KQPASKATSD 660
KTDSALNIAT EIKDGLQCGT VSSQKQPALK ATTDEEDSVS NIATEIKDGE KSGTVSSQKQ 720
PALKATTDEE DSVSNIATEI KDGEKSGTVS SQKQPALKAT TDEKDSVSNI ATEIKDGEKS 780
GTVSSQKPPA LTATSDEEGS VLSIARENKD GEKSRTVSSR KKPALKATSD EKDSFSNITR 840
GKKDGEISRK VSSQKPPTLK GTSDEEDSVL GIARENKDGE KSRTVSSEKP PGLKASSAEK 900
DSVLNIARGK KDGEKTKRVS SRKKPSLEAT SDEKDSFSNI TREKKDGEIS RKVSSQKPPA 960
LKGTSDEEDS VLGIARENKD GEKSRTVSSE KPPGLKATSD EKDSVLNIAR GKKDGEKTRT 1020
VSSQKPPTLK ATSDEEDSVL SIARENKDGE KSRTVSSEKP SGLKATSAEK DSVLNIARGK 1080
KYGEKTKRVS SRKKPALKAT SDEKDSVLYI AREKKDGEKS RTVSSPKQPA LKAICDKEDS 1140
VPNMATEKKD EQISGTVSCQ KQPALKATSD KKDSVSNIPT EIKDGQQSGT VSSQKQPAWK 1200
ATSVKKDSVS NIATEIKDGQ IRGTGILEYT FNVMFDQIEE KFTSLNKSAG VSPQKQSAQK 1260
VIFKKKVSLL NIATRITGGW KSGTEYPENL PTLKATIENK NSVLNTATKM KDVQTSTPAE 1320
QDLEMASEGE QKRLEEYENN QPQVKNQIHS RDDLDDIIQS SQTVSEDGDS LCCNCKNVIL 1380
LIDQHEMKCK DCVHLLKIKN TFCLWKRLIK LKDNHCEQLR VKIRKLKNKA SVLQKRISEK 1440
EEIKSQLKHE ILELEKELCS LRFAIQQEKK KRRNVEEVHQ KVREKLRITE EQYRIEADVT 1500
KPIKPALKSA EVELKTGGNN SNQVSETDEK EDLLHENRLM QDEIARLRLE KDTIKNQNLE 1560
KKYLKDFEIV KRKHEDLQKA LKRNGETLAK TIACYSGQLA ALTDENTTLR SKLEKQRESR 1620
QRLETEMQSY HCRLNAARCD HDQSHSSKRD QELAFQGTVD KCRHLQENLN SHVLILSLQL 1680
SKAESKSRVL KTELHYTGEA LKEKALVFEH VQSELKQKQS QMKDIEKMYK SGYNTMEKCI 1740
EKQERFCQLK KQNMLLQQQL DDARNKADNQ EKAILNIQAR CDARVQNLQA ECRKHRLLLE 1800
EDNKMLVNEL NHSKEKECQY EKEKAEREVA VRQLQQKRDD VLNKGSATKA LLDASSRHCT 1860
YLENGMQDSR KKLDQMRSQF QEIQDQLTAT IRCTKEMEGD TQKLEVEHVM MRKIIKKQDD 1920
QIERLEKILQ HSSLMLQVFE S 1941 
Gene Ontology
  
Interpro
 IPR002110; Ankyrin_rpt.
 IPR020683; Ankyrin_rpt-contain_dom. 
Pfam
 PF00023; Ank
 PF12796; Ank_2 
SMART
 SM00248; ANK 
PROSITE
 PS50297; ANK_REP_REGION
 PS50088; ANK_REPEAT 
PRINTS