CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-037536
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Ribosome biogenesis protein BOP1 
Protein Synonyms/Alias
  
Gene Name
 BOP1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
19APSVRPEKRRSEPELacetylation[1]
91LDGRRIYKPLRTRDEubiquitination[2]
105ELDQFLDKMDDPDYWubiquitination[3]
183FIPSLVEKEKVSRMVubiquitination[1, 2, 3, 4]
185PSLVEKEKVSRMVHAubiquitination[1, 2]
194SRMVHAIKMGWIQPRubiquitination[2]
269QQEPGERKLSFLPRKubiquitination[1, 2]
Reference
 [1] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302]
 [2] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [3] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [4] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 312 AA 
Protein Sequence
MAGSRGAGRT AAPSVRPEKR RSEPELEPEP EPEASTPCPR TEMASARIGD EYAEDSSDEE 60
DIRNTVGNVP LEWYDDFPHV GYDLDGRRIY KPLRTRDELD QFLDKMDDPD YWRTVQDPMT 120
GRDLRLTDEQ VALVRRLQSG QFGDVGFNPY EPAVDFFSGD VMIHPVTNRP ADKRSFIPSL 180
VEKEKVSRMV HAIKMGWIQP RRPRDPTPSF YDLWAQEDPN AVLGRHKMHV PAPKLALPGH 240
AESYNPPPEY LLSEEERLAW EQQEPGERKL SFLPRKFPSL RAVPAYGRFI QERFERCLDL 300
YLCPRQRKMR VC 312 
Gene Ontology
 GO:0006364; P:rRNA processing; IEA:InterPro. 
Interpro
 IPR012953; BOP1_N_dom. 
Pfam
 PF08145; BOP1NT 
SMART
 SM01035; BOP1NT 
PROSITE
  
PRINTS