CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-015432
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 UPF0577 protein KIAA1324 
Protein Synonyms/Alias
 Estrogen-induced gene 121 protein 
Gene Name
 KIAA1324 
Gene Synonyms/Alias
 EIG121; UNQ2426/PRO4985 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
254TAFSVWTKVPKPVLVacetylation[1]
279TSECFPCKPGTYADKacetylation[1]
Reference
 [1] Regulation of cellular metabolism by protein lysine acetylation.
 Zhao S, Xu W, Jiang W, Yu W, Lin Y, Zhang T, Yao J, Zhou L, Zeng Y, Li H, Li Y, Shi J, An W, Hancock SM, He F, Qin L, Chin J, Yang P, Chen X, Lei Q, Xiong Y, Guan KL.
 Science. 2010 Feb 19;327(5968):1000-4. [PMID: 20167786] 
Functional Description
 May play a role as a marker of hyperestrogenic state and estrogen-related type I endometrial carcinoma. 
Sequence Annotation
 CARBOHYD 153 153 N-linked (GlcNAc...) (Potential).
 CARBOHYD 404 404 N-linked (GlcNAc...) (Potential).
 CARBOHYD 672 672 N-linked (GlcNAc...) (Potential).
 DISULFID 278 295 By similarity.
 DISULFID 308 330 By similarity.
 DISULFID 311 342 By similarity.  
Keyword
 Alternative splicing; Complete proteome; Disulfide bond; Glycoprotein; Membrane; Polymorphism; Reference proteome; Signal; Transmembrane; Transmembrane helix. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1013 AA 
Protein Sequence
MAEPGHSHHL SARVRGRTER RIPRLWRLLL WAGTAFQVTQ GTGPELHACK ESEYHYEYTA 60
CDSTGSRWRV AVPHTPGLCT SLPDPIKGTE CSFSCNAGEF LDMKDQSCKP CAEGRYSLGT 120
GIRFDEWDEL PHGFASLSAN MELDDSAAES TGNCTSSKWV PRGDYIASNT DECTATLMYA 180
VNLKQSGTVN FEYYYPDSSI IFEFFVQNDQ CQPNADDSRW MKTTEKGWEF HSVELNRGNN 240
VLYWRTTAFS VWTKVPKPVL VRNIAITGVA YTSECFPCKP GTYADKQGSS FCKLCPANSY 300
SNKGETSCHQ CDPDKYSEKG SSSCNVRPAC TDKDYFYTHT ACDANGETQL MYKWAKPKIC 360
SEDLEGAVKL PASGVKTHCP PCNPGFFKTN NSTCQPCPYG SYSNGSDCTR CPAGTEPAVG 420
FEYKWWNTLP TNMETTVLSG INFEYKGMTG WEVAGDHIYT AAGASDNDFM ILTLVVPGFR 480
PPQSVMADTE NKEVARITFV FETLCSVNCE LYFMVGVNSR TNTPVETWKG SKGKQSYTYI 540
IEENTTTSFT WAFQRTTFHE ASRKYTNDVA KIYSINVTNV MNGVASYCRP CALEASDVGS 600
SCTSCPAGYY IDRDSGTCHS CPTNTILKAH QPYGVQACVP CGPGTKNNKI HSLCYNDCTF 660
SRNTPTRTFN YNFSALANTV TLAGGPSFTS KGLKYFHHFT LSLCGNQGRK MSVCTDNVTD 720
LRIPEGESGF SKSITAYVCQ AVIIPPEVTG YKAGVSSQPV SLADRLIGVT TDMTLDGITS 780
PAELFHLESL GIPDVIFFYR SNDVTQSCSS GRSTTIRVRC SPQKTVPGSL LLPGTCSDGT 840
CDGCNFHFLW ESAAACPLCS VADYHAIVSS CVAGIQKTTY VWREPKLCSG GISLPEQRVT 900
ICKTIDFWLK VGISAGTCTA ILLTVLTCYF WKKNQKLEYK YSKLVMNATL KDCDLPAADS 960
CAIMEGEDVE DDLIFTSKKS LFGKIKSFTS KRTPDGFDSV PLKTSSGGLD MDL 1013 
Gene Ontology
 GO:0005887; C:integral to plasma membrane; IDA:BHF-UCL.
 GO:0016236; P:macroautophagy; IMP:BHF-UCL.
 GO:0043066; P:negative regulation of apoptotic process; IMP:BHF-UCL.
 GO:2000786; P:positive regulation of autophagic vacuole assembly; IMP:BHF-UCL. 
Interpro
 IPR009030; Growth_fac_rcpt_N_dom.
 IPR009011; Man6P_isomerase_rcpt-bd_dom. 
Pfam
  
SMART
  
PROSITE
  
PRINTS