CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-016530
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Cell growth regulator with RING finger domain protein 1 
Protein Synonyms/Alias
 Cell growth regulatory gene 19 protein 
Gene Name
 Cgrrf1 
Gene Synonyms/Alias
 Cgr19 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
113KLYEALQKHAYCFRIubiquitination[1]
256VEQSLLEKVGLAGNDubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023
Functional Description
 Able to inhibit growth in several cell lines (By similarity). 
Sequence Annotation
 ZN_FING 274 309 RING-type.  
Keyword
 Cell cycle; Complete proteome; Growth arrest; Metal-binding; Nucleus; Reference proteome; Zinc; Zinc-finger. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 332 AA 
Protein Sequence
MAAVFLVTLY EYSPLFYIAV VFTCFIVTTG LVLGWFGWDV PVILRNSEET QFSTRAFKKQ 60
MRQVKNPFGL EITNSSAASL ATGMALRTDC LEDSRLTCYW GCSVQKLYEA LQKHAYCFRI 120
STPQALEEAL YSDYLHREQY FIKKHSKEEI YCQLPSDTEI EDFGPVPRSR YPLVALLTLA 180
DEDDREIYDI ISMVSVIHIP DKTYKLPCRI LYQYLILAQG QFYDLKQLFM SANNSPPPSN 240
DESPEDRSVE QSLLEKVGLA GNDGDPVEES SRDCVVCQNG GVNWVLLPCR HACLCDSCVR 300
YFKQCPMCRQ FVQESFALCG QKEPDKDLLE TS 332 
Gene Ontology
 GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
 GO:0008270; F:zinc ion binding; IEA:InterPro.
 GO:0007050; P:cell cycle arrest; IEA:UniProtKB-KW. 
Interpro
 IPR001841; Znf_RING.
 IPR013083; Znf_RING/FYVE/PHD. 
Pfam
  
SMART
 SM00184; RING 
PROSITE
 PS00518; ZF_RING_1
 PS50089; ZF_RING_2 
PRINTS