CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-035022
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Tripartite motif-containing protein 2 
Protein Synonyms/Alias
  
Gene Name
 Trim2 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
500VGTKGRNKGEFTNLQubiquitination[1]
Reference
 [1] Synaptic protein ubiquitination in rat brain revealed by antibody-based ubiquitome analysis.
 Na CH, Jones DR, Yang Y, Wang X, Xu Y, Peng J.
 J Proteome Res. 2012 Sep 7;11(9):4722-32. [PMID: 22871113
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Metal-binding; Reference proteome; Zinc; Zinc-finger. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 761 AA 
Protein Sequence
QRAGSRTAGP TCQWSRMASE GASIPSPVVR QIDKQFLICS ICLERYKNPK VLPCLHTFCE 60
SCQLSSVSLS PSAKVRGHIG AQTSILPEKG VAALQNNFFI TNLMDVLQRT PGSNGEDPSI 120
LQTVTAVAAG KPLSCPNHDG NVMEFYCQSC ETAMCRECTE GEHAEHPTVP LKDVVEQHKA 180
SLQVQLDAVN KRLPEIDSAL QFISEIIHQL TNQKASIVDD IHSTFDELQK TLNVRKSVLL 240
MELEVNYGLK HKVLQSQLDT LLQGQESIKS CSNFTAQALN HGTETEVLLV KKQMSEKLNE 300
LADQDFPLHP RENDQLDFIV ETEGLKKSIH NLGTILTTNA VASETVATGE GLRQTIIGQP 360
MSVTITTKDK DGELCKTGNA YLTAELSTPD GSVADGEILD NKNGTYEFLY TVQKEGDFTL 420
SLRLYDQHIR GSPFKLKVIR SADVSPTTEG VKRRVKSPGS GHVKQKAVKR PASMYSTGKR 480
KENPIEDDLI FRVGTKGRNK GEFTNLQGVA ASTSGKILIA DSNNQCVQIF SNDGQFKSRF 540
GIRGRSPGQL QRPTGVAVHP SGDIIIADYD NKWVSIFSND GKFKTKIGSG KLMGPKGVSV 600
DRNGHIIVVD NKACCVFIFQ PNGKIVTRFG SRGNGDRQFA GPHFAAVNSS NEIIITDFHN 660
HSVKVFNQEG EFMLKFGSNG EGNGQFNAPT GVAVDSNGNI IVADWGNSRI QVFDGSGSFL 720
SYINTSADPL YGPQGLALTS DGHVVVADSG NHCFKVYRYL Q 761 
Gene Ontology
 GO:0005622; C:intracellular; IEA:InterPro.
 GO:0008270; F:zinc ion binding; IEA:InterPro. 
Interpro
 IPR011042; 6-blade_b-propeller_TolB-like.
 IPR003649; Bbox_C.
 IPR001298; Filamin.
 IPR017868; Filamin/ABP280_repeat-like.
 IPR013783; Ig-like_fold.
 IPR014756; Ig_E-set.
 IPR001258; NHL_repeat.
 IPR013017; NHL_repeat_subgr.
 IPR000315; Znf_B-box.
 IPR018957; Znf_C3HC4_RING-type.
 IPR001841; Znf_RING.
 IPR013083; Znf_RING/FYVE/PHD. 
Pfam
 PF00630; Filamin
 PF01436; NHL
 PF00643; zf-B_box
 PF00097; zf-C3HC4 
SMART
 SM00502; BBC
 SM00336; BBOX
 SM00557; IG_FLMN
 SM00184; RING 
PROSITE
 PS50194; FILAMIN_REPEAT
 PS51125; NHL
 PS50119; ZF_BBOX
 PS50089; ZF_RING_2 
PRINTS