| Tag | Content |
|---|
| CPLM ID | CPLM-016000 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Triosephosphate isomerase |
Protein Synonyms/Alias | TIM; Triose-phosphate isomerase |
Gene Name | tpi1 |
Gene Synonyms/Alias | tpi |
Created Date | July 27, 2013 |
Organism | Xenopus laevis (African clawed frog) |
NCBI Taxa ID | 8355 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 130 | VIACIGEKLDQREAG | acetylation | [1] | | 141 | REAGITEKVVFEQTK | acetylation | [1] | | 155 | KAIADNVKDWSKVVL | acetylation | [1] |
|
Reference | [1] A biotin switch-based proteomics approach identifies 14-3-3ΞΆ as a target of Sirt1 in the metabolic regulation of caspase-2. Andersen JL, Thompson JW, Lindblom KR, Johnson ES, Yang CS, Lilley LR, Freel CD, Moseley MA, Kornbluth S. Mol Cell. 2011 Sep 2;43(5):834-42. [ PMID: 21884983] |
Functional Description | |
Sequence Annotation | ACT_SITE 95 95 Electrophile (By similarity).
ACT_SITE 165 165 Proton acceptor (By similarity).
BINDING 11 11 Substrate (By similarity).
BINDING 13 13 Substrate (By similarity). |
Keyword | Gluconeogenesis; Glycolysis; Isomerase; Pentose shunt. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 248 AA |
Protein Sequence | MSPRKFFVGG NWKMNGDKKS LGELINTLNS GKMNADTEVV CGAPAIYLDF ARQKLDAKIA 60
LSAQNCYKVA KGAFTGEISP AMIKDCGATW VILGHSERRH VFGECDELIG QKVAHALSEG 120
IGVIACIGEK LDQREAGITE KVVFEQTKAI ADNVKDWSKV VLAYEPVWAI GTGKTATPEQ 180
AQEVHKKLRE WVKTNVSEGV AQSVRIIYGG SVTGGTCREL AGQPDIDGFL VGGASLKPEF 240
IEIINAKH 248 |
Gene Ontology | GO:0004807; F:triose-phosphate isomerase activity; IEA:EC. GO:0006094; P:gluconeogenesis; IEA:UniProtKB-UniPathway. GO:0006096; P:glycolysis; IEA:UniProtKB-UniPathway. GO:0006098; P:pentose-phosphate shunt; IEA:UniProtKB-KW. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |