CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-013950
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Putative hydroxypyruvate isomerase 
Protein Synonyms/Alias
 Endothelial cell apoptosis protein E-CE1 
Gene Name
 HYI 
Gene Synonyms/Alias
 HT036; SB156 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
71TPPGDQEKGEMGLGAubiquitination[1]
Reference
 [1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983] 
Functional Description
 Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity). 
Sequence Annotation
  
Keyword
 Alternative splicing; Complete proteome; Isomerase; Polymorphism; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 277 AA 
Protein Sequence
MAPLRFSANL SWLFPELSGL PARVRAAGSS GFEAVEVAWP YAETPEALAR AAREAGLRLV 60
LINTPPGDQE KGEMGLGAVP GRQAAFREGL EQAVRYAKAL GCPRIHLMAG RVPQGADRIA 120
VKAEMEAVFL ENLRHAAGVL AQEDLVGLLE PINTRITDPQ YFLDTPQQAA AILQKVGRPN 180
LQLQMDIFHW QIMDGNLTGN IREFLPIVGH VQVAQVPGRG EPSSPGELNF PYLFQLLEDE 240
GYKGFVGCEY QPRGDTVEGL SWLRSYWDRR GHPEAGQ 277 
Gene Ontology
 GO:0008903; F:hydroxypyruvate isomerase activity; IEA:EC. 
Interpro
 IPR026040; HyI-like.
 IPR013022; Xyl_isomerase-like_TIM-brl. 
Pfam
 PF01261; AP_endonuc_2 
SMART
  
PROSITE
  
PRINTS