CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-031461
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Soluble interleukin-4 receptor subunit alpha 
Protein Synonyms/Alias
 cDNA FLJ58656, highly similar to Interleukin-4 receptor alpha chain 
Gene Name
 IL4R 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
177RIAASTLKSGISYRAubiquitination[1]
Reference
 [1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Receptor; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 810 AA 
Protein Sequence
MQKDARREGN MKVLQEPTCV SDYMSISTCE WKMNGPTNCS TELRLLYQLV FLLSEAHTCI 60
PENNGGAGCV CHLLMDDVVS ADNYTLDLWA GQQLLWKGSF KPSEHVKPRA PGNLTVHTNV 120
SDTLLLTWSN PYPPDNYLYN HLTYAVNIWS ENDPADFRIY NVTYLEPSLR IAASTLKSGI 180
SYRARVRAWA QCYNTTWSEW SPSTKWHNSY REPFEQHLLL GVSVSCIVIL AVCLLCYVSI 240
TKIKKEWWDQ IPNPARSRLV AIIIQDAQGS QWEKRSRGQE PAKCPHWKNC LTKLLPCFLE 300
HNMKRDEDPH KAAKEMPFQG SGKSAWCPVE ISKTVLWPES ISVVRCVELF EAPVECEEEE 360
EVEEEKGSFC ASPESSRDDF QEGREGIVAR LTESLFLDLL GEENGGFCQQ DMGESCLLPP 420
SGSTSAHMPW DEFPSAGPKE APPWGKEQPL HLEPSPPASP TQSPDNLTCT ETPLVIAGNP 480
AYRSFSNSLS QSPCPRELGP DPLLARHLEE VEPEMPCVPQ LSEPTTVPQP EPETWEQILR 540
RNVLQHGAAA APVSAPTSGY QEFVHAVEQG GTQASAVVGL GPPGEAGYKA FSSLLASSAV 600
SPEKCGFGAS SGEEGYKPFQ DLIPGCPGDP APVPVPLFTF GLDREPPRSP QSSHLPSSSP 660
EHLGLEPGEK VEDMPKPPLP QEQATDPLVD SLGSGIVYSA LTCHLCGHLK QCHGQEDGGQ 720
TPVMASPCCG CCCGDRSSPP TTPLRAPDPS PGGVPLEASL CPASLAPSGI SEKSKSSSSF 780
HPAPGNAQSS SQTPKIVNFV SVGPTYMRVS 810 
Gene Ontology
 GO:0016021; C:integral to membrane; IEA:InterPro.
 GO:0004896; F:cytokine receptor activity; IEA:InterPro.
 GO:0019221; P:cytokine-mediated signaling pathway; IEA:GOC.
 GO:0002532; P:production of molecular mediator involved in inflammatory response; IEA:InterPro. 
Interpro
 IPR003961; Fibronectin_type3.
 IPR003531; Hempt_rcpt_S_F1_CS.
 IPR013783; Ig-like_fold.
 IPR015319; IL4Ra_N. 
Pfam
 PF09238; IL4Ra_N 
SMART
 SM00060; FN3 
PROSITE
 PS50853; FN3
 PS01355; HEMATOPO_REC_S_F1 
PRINTS