UniProt Accession

 APQ12_YEAST; P40532; D6VVP2 

Genbank Protein ID

 Z46861; BK006942 

Genbank Nucleotide ID

 CAA86911.1; DAA08508.1 

Protein Name

 Nuclear membrane organization protein APQ12 

Protein Synonyms/Alias

  

Gene Name

 APQ12 

Gene Synonyms/Alias

 YIL040W 

Created Date

 July 27, 2013 

Organism

 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 

NCBI Taxa ID

 559292 

Lysine Modification

Position	Peptide	Type	References
66	MNFITLVKRFLYLTL	ubiquitination	[1]

Reference

 [1] Sites of ubiquitin attachment in Saccharomyces cerevisiae.
 Starita LM, Lo RS, Eng JK, von Haller PD, Fields S.
 Proteomics. 2012 Jan;12(2):236-40. [PMID: 22106047] 

Functional Description

 Involved in the regulation of lipid homeostasis in the endoplasmic reticulum, thereby impacting nuclear pore complex biogenesis and localization, and nucleocytoplasmic mRNA transport. 

Sequence Annotation

  

Keyword

 Complete proteome; Endoplasmic reticulum; Membrane; mRNA transport; Nucleus; Reference proteome; Transmembrane; Transmembrane helix; Transport. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 138 AA 

Protein Sequence

Gene Ontology

 GO:0005783; C:endoplasmic reticulum; IDA:SGD.
 GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0005635; C:nuclear envelope; IDA:SGD.
 GO:0031965; C:nuclear membrane; IEA:UniProtKB-SubCell.
 GO:0044255; P:cellular lipid metabolic process; IGI:SGD.
 GO:0006406; P:mRNA export from nucleus; IMP:SGD.
 GO:0006998; P:nuclear envelope organization; IMP:SGD. 

Interpro

 IPR024316; APQ12. 

Pfam

 PF12716; Apq12 

SMART

  

PROSITE

  

PRINTS