CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-031855
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Ap endonuclease, putative 
Protein Synonyms/Alias
 DNA-(Apurinic or apyrimidinic site) lyase, putative 
Gene Name
 TGME49_016600, TGVEG_037690 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Toxoplasma gondii 
NCBI Taxa ID
 5811 
Lysine Modification
Position
Peptide
Type
References
622ALHASLEKPRNVQASacetylation[1]
Reference
 [1] Protein intrinsic disorder in the acetylome of intracellular and extracellular Toxoplasma gondii.
 Xue B, Jeffers V, Sullivan WJ, Uversky VN.
 Mol Biosyst. 2013 Apr 5;9(4):645-57. [PMID: 23403842
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Endonuclease; Hydrolase; Lyase; Nuclease; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 630 AA 
Protein Sequence
MRPLGSFLPS FVHFDWTFCR GLPLAENLPV SKVTLRRLEP PFASSLAVYS PSALSLSSPP 60
FCLILPASLS GSSAFSSSRS RPGPQPSPAA AGARTRNSQR TSTMSVHRAV NSAQGEEETE 120
GPHRETTTEL NSSAASLSSS PSSAPSCSVS TSAMLQRASD SSSSGAPPVD LNPSRETRET 180
EEDGEGELER RTEGPKRKAP LSIVTWNVNS IAARIRDSRQ WFYFSRFLQK IDPDILCLQE 240
VKLAAHGPPG AKRGDGMPRD HGRIKDSDKV SSVEARELRE ALHTLLPNHS LLISLADWRY 300
SGQMMFIRKD VQVCSLRYNL SLDGCPAHEH DFEGRVILAE FEAFCVLTTY SPNNGATPKS 360
FERRRLWDER MLQFVTQCSS SPHCEGLPVQ LLKKPLVWVG DLNCAPEDID LSDPDQFRSV 420
IHETADGTID PDNIGQAGCT DAERRRFRAI LERGNLVDAF RELHPRTEPP PLESAEYSWR 480
GFGGSGSRGL LRGLGMRLDH IVLTETLMPA VELVRICGAG KSKANFFGSD HCPVLVLFKE 540
KEISALPAVV CEALRSSAPA PAAKKRQDDC RLDSFFAVKR RAQLPGAADQ KRKKPEEVVI 600
SDSSDEERKT SQKIALHASL EKPRNVQASS 630 
Gene Ontology
 GO:0005622; C:intracellular; IEA:InterPro.
 GO:0003677; F:DNA binding; IEA:InterPro.
 GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.
 GO:0008853; F:exodeoxyribonuclease III activity; IEA:EC.
 GO:0016829; F:lyase activity; IEA:UniProtKB-KW.
 GO:0006281; P:DNA repair; IEA:InterPro.
 GO:0090305; P:nucleic acid phosphodiester bond hydrolysis; IEA:GOC. 
Interpro
 IPR020847; AP_endonuclease_F1_BS.
 IPR005135; Endo/exonuclease/phosphatase.
 IPR004808; ExoDNase_III. 
Pfam
 PF03372; Exo_endo_phos 
SMART
  
PROSITE
 PS00726; AP_NUCLEASE_F1_1
 PS51435; AP_NUCLEASE_F1_4 
PRINTS