UniProt Accession

 Q7KN99_DROME; Q7KN99 

Genbank Protein ID

 AF132150; AE014297; AE014297 

Genbank Nucleotide ID

 AAD34738.1; AAF55637.1; AAN13797.1 

Protein Name

 Phosphopantothenoylcysteine synthetase, isoform A 

Protein Synonyms/Alias

 Phosphopantothenoylcysteine synthetase, isoform B 

Gene Name

 Ppcs 

Gene Synonyms/Alias

 CG5629; Dmel_CG5629 

Created Date

 July 27, 2013 

Organism

 Drosophila melanogaster (Fruit fly) 

NCBI Taxa ID

 7227 

Lysine Modification

Position	Peptide	Type	References
88	VIFMHRHKSLEPFTR	acetylation	[1]
248	KARDSLNKYKHKLVI	acetylation	[1]

Reference

 [1] Proteome-wide mapping of the Drosophila acetylome demonstrates a high degree of conservation of lysine acetylation.
 Weinert BT, Wagner SA, Horn H, Henriksen P, Liu WR, Olsen JV, Jensen LJ, Choudhary C.
 Sci Signal. 2011 Jul 26;4(183):ra48. [PMID: 21791702] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Ligase; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 313 AA 

Protein Sequence

Gene Ontology

 GO:0004632; F:phosphopantothenate--cysteine ligase activity; ISA:FlyBase.
 GO:0030036; P:actin cytoskeleton organization; IMP:FlyBase.
 GO:0022416; P:chaeta development; IMP:FlyBase.
 GO:0015937; P:coenzyme A biosynthetic process; ISA:FlyBase.
 GO:0007303; P:cytoplasmic transport, nurse cell to oocyte; IMP:FlyBase.
 GO:0046843; P:dorsal appendage formation; IMP:FlyBase.
 GO:0030708; P:germarium-derived female germ-line cyst encapsulation; IMP:FlyBase.
 GO:0007476; P:imaginal disc-derived wing morphogenesis; IMP:FlyBase.
 GO:0007297; P:ovarian follicle cell migration; IMP:FlyBase.
 GO:0030713; P:ovarian follicle cell stalk formation; IMP:FlyBase.
 GO:0055091; P:phospholipid homeostasis; IMP:FlyBase.
 GO:0070328; P:triglyceride homeostasis; IMP:FlyBase. 

Interpro

 IPR007085; DNA/pantothenate-metab_flavo_C. 

Pfam

 PF04127; DFP 

SMART

  

PROSITE

  

PRINTS