CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-034912
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Dynamin-3 
Protein Synonyms/Alias
  
Gene Name
 Dnm3 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
191SDALKLAKEVDPQGLacetylation[1]
257AAMLAERKFFLSHPAacetylation[1]
299TLPNFRNKLQGQLLSacetylation[1]
393REISYAIKNIHGIRTubiquitination[2]
568DDEEKEKKYMLPLDNacetylation[1]
604TEQRNVYKDYRSLELacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405]
 [2] Synaptic protein ubiquitination in rat brain revealed by antibody-based ubiquitome analysis.
 Na CH, Jones DR, Yang Y, Wang X, Xu Y, Peng J.
 J Proteome Res. 2012 Sep 7;11(9):4722-32. [PMID: 22871113] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; GTP-binding; Nucleotide-binding; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 878 AA 
Protein Sequence
MGNREMEELI PLVNRLQDAF SALGQSCLLE LPQIAVVGGQ SAGKSSVLEN FVGRDFLPRG 60
SGIVTRRPLV LQLVTSKAEY AEFLHCKGKK FTDFDEVRHE IEAETDRVTG MNKGISSVPI 120
NLRVYSPHVL NLTLIDLPGI TKVPVGDQPP DIEYQIRDMI MQFITRENCL ILAVTPANTD 180
LANSDALKLA KEVDPQGLRT IGVITKLDLM DEGTDARDVL ENKLLPLRRG YVGVVNRSQK 240
DIDGKKDIKA AMLAERKFFL SHPAYRHIAD RMGTPHLQKV LNQQLTNHIR DTLPNFRNKL 300
QGQLLSIEHE VEAFKNFKPE DPTRKTKALL QMVQQFAVDF EKRIEGSGDQ VDTLELSGGA 360
KINRIFHERF PFEIVKMEFN EKELRREISY AIKNIHGIRT GLFTPDMAFE AIVKKQIVKL 420
KGPSLKSVDL VMQELINTVK KCTKRLANFP RLCEETERIV ANHIREREGK TKDQVLLLID 480
IQVSYINTNH EDFIGFANAQ QRSSQVHKKS TIGNQGTNLP PSRQIVIRKG WLTVSNIGIM 540
KGGSKGYWFV LTAESLSWYK DDEEKEKKYM LPLDNLKVRD VEKGFMSSKH VFALFNTEQR 600
NVYKDYRSLE LACDSQEDVD SWKASLLRAG VYPDKSFVTS EKGGKETEND ENGQAENFSM 660
DPQLERQVET IRNLVDSYMS IINKCIRDLI PKTIMHLMIN NVKDFINSEL LAQLYSSEDQ 720
NTLMEESVEQ AQRRDEMLRM YQALKEALAI IGDINTVTVS TPAPPPVDDS WLQHSRRSPP 780
PSPTTQRRLT LSAPLPRPAS SRGPAPAIPS PGPHSGAPPV PFRPGPLPPF PNSSDSYGAP 840
PQVPSRPTRA PPSVPSRRPP PSPTRPTIIR PLESSLLD 878 
Gene Ontology
 GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
 GO:0003924; F:GTPase activity; IEA:InterPro.
 GO:0005543; F:phospholipid binding; IEA:InterPro.
 GO:0006184; P:GTP catabolic process; IEA:GOC. 
Interpro
 IPR022812; Dynamin.
 IPR000375; Dynamin_central.
 IPR001401; Dynamin_GTPase.
 IPR019762; Dynamin_GTPase_CS.
 IPR003130; GED.
 IPR020850; GTPase_effector_domain_GED.
 IPR027417; P-loop_NTPase.
 IPR011993; PH_like_dom.
 IPR001849; Pleckstrin_homology. 
Pfam
 PF01031; Dynamin_M
 PF00350; Dynamin_N
 PF02212; GED
 PF00169; PH 
SMART
 SM00053; DYNc
 SM00302; GED
 SM00233; PH 
PROSITE
 PS00410; DYNAMIN
 PS51388; GED
 PS50003; PH_DOMAIN 
PRINTS
 PR00195; DYNAMIN.