| Tag | Content |
|---|
| CPLM ID | CPLM-020268 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | ADP-ribose pyrophosphatase, mitochondrial |
Protein Synonyms/Alias | ADP-ribose diphosphatase; ADP-ribose phosphohydrolase; Adenosine diphosphoribose pyrophosphatase; ADPR-PPase; Nucleoside diphosphate-linked moiety X motif 9; Nudix motif 9 |
Gene Name | NUDT9 |
Gene Synonyms/Alias | NUDT10; PSEC0099; UNQ3012/PRO9771 |
Created Date | July 27, 2013 |
Organism | Homo sapiens (Human) |
NCBI Taxa ID | 9606 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 310 | GDDAGKVKWVDINDK | acetylation | [1] |
|
Reference | [1] Proteomic investigations of lysine acetylation identify diverse substrates of mitochondrial deacetylase sirt3. Sol EM, Wagner SA, Weinert BT, Kumar A, Kim HS, Deng CX, Choudhary C. PLoS One. 2012;7(12):e50545. [ PMID: 23236377] |
Functional Description | Hydrolyzes ADP-ribose (ADPR) to AMP and ribose 5'- phosphate. |
Sequence Annotation | DOMAIN 178 334 Nudix hydrolase.
MOTIF 215 237 Nudix box.
MOD_RES 121 121 Phosphoserine. |
Keyword | 3D-structure; Alternative splicing; Complete proteome; Hydrolase; Magnesium; Manganese; Mitochondrion; Phosphoprotein; Reference proteome; Transit peptide. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 350 AA |
Protein Sequence | MAGRLLGKAL AAVSLSLALA SVTIRSSRCR GIQAFRNSFS SSWFHLNTNV MSGSNGSKEN 60
SHNKARTSPY PGSKVERSQV PNEKVGWLVE WQDYKPVEYT AVSVLAGPRW ADPQISESNF 120
SPKFNEKDGH VERKSKNGLY EIENGRPRNP AGRTGLVGRG LLGRWGPNHA ADPIITRWKR 180
DSSGNKIMHP VSGKHILQFV AIKRKDCGEW AIPGGMVDPG EKISATLKRE FGEEALNSLQ 240
KTSAEKREIE EKLHKLFSQD HLVIYKGYVD DPRNTDNAWM ETEAVNYHDE TGEIMDNLML 300
EAGDDAGKVK WVDINDKLKL YASHSQFIKL VAEKRDAHWS EDSEADCHAL 350 |
Gene Ontology | GO:0005759; C:mitochondrial matrix; TAS:Reactome. GO:0043262; F:adenosine-diphosphatase activity; IEA:Compara. GO:0047631; F:ADP-ribose diphosphatase activity; EXP:Reactome. GO:0019144; F:ADP-sugar diphosphatase activity; NAS:UniProtKB. GO:0046032; P:ADP catabolic process; IEA:Compara. GO:0046709; P:IDP catabolic process; IEA:Compara. GO:0034656; P:nucleobase-containing small molecule catabolic process; TAS:Reactome. |
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PROSITE | |
PRINTS | |