CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-015448
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Glycerophosphodiester phosphodiesterase domain-containing protein 4 
Protein Synonyms/Alias
 Glycerophosphodiester phosphodiesterase 6; UgpQ 
Gene Name
 GDPD4 
Gene Synonyms/Alias
 GDE6; UGPQ 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
296LRPFYNMKPLSEADKmethylation[1]
303KPLSEADKERARNQSmethylation[1]
Reference
 [1] Large-scale global identification of protein lysine methylation in vivo.
 Cao XJ, Arnaudo AM, Garcia BA.
 Epigenetics. 2013 May 1;8(5):477-85. [PMID: 23644510
Functional Description
  
Sequence Annotation
 DOMAIN 203 452 GDPD.
 METAL 230 230 Divalent metal cation (Potential).
 METAL 232 232 Divalent metal cation (Potential).
 METAL 245 245 Divalent metal cation (Potential).
 CARBOHYD 308 308 N-linked (GlcNAc...) (Potential).
 CARBOHYD 397 397 N-linked (GlcNAc...) (Potential).  
Keyword
 Alternative splicing; Complete proteome; Glycoprotein; Hydrolase; Membrane; Metal-binding; Polymorphism; Reference proteome; Transmembrane; Transmembrane helix. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 623 AA 
Protein Sequence
MLLFLWIETS SEYFNFDWVT FLGTGYWFFW SIFILSLARI LTAYSSLLLL LGFLLLWERI 60
ELYLHLCHKI LILLVILLCV ILMFIICKFW KERWLVAGLS MQIFAPYVHL VSITVMVILF 120
WPVAFYVACL EREVRMRRYR MTHSEKKRLK QCNVITRLRG LQVPVGLPFL LILLGLYLMP 180
LGIYSPCIQE KENLGPKPTI FGHRGAPMLG PENTMMSFEK AVEHGAHGLE TDIHLSYDHV 240
PFLMHDFDLK RTTNIGEVQP ESACENPAFF NWDFLSTLNA GKWFVKPELR PFYNMKPLSE 300
ADKERARNQS IPTLADLLTL AEKERKFVIF DLHRPPPKHP LRHTFVRQVV SVILASKIEQ 360
HLIFWLPAHD RQYVRSVAPG FQHVGRLVSI ETLAKNNISI INVDYKKLFP NGLRDYKAAN 420
IHINVYTVNE PWLFSLAWCS RINSVTTDNI GLLSQLDHPH FFMTPKFYVF MWLLADIISV 480
LFIVAIFCFH WRRETEKEKL FETSSTRTDT QSGNLHIAMK PPVRVVEGPW TLAALYPALP 540
KSGKEHQGHF NFAAPSKKLL PIKNAVTPLK PGKHEIQPPM PTVVFELTQA PTRQATSEAT 600
FQTTLPTLKV DKPTMPSIEV PYP 623 
Gene Ontology
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0008889; F:glycerophosphodiester phosphodiesterase activity; IEA:InterPro.
 GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
 GO:0006071; P:glycerol metabolic process; IEA:InterPro.
 GO:0006629; P:lipid metabolic process; IEA:InterPro. 
Interpro
 IPR004129; GlyceroP-diester-Pdiesterase.
 IPR017946; PLC-like_Pdiesterase_TIM-brl. 
Pfam
 PF03009; GDPD 
SMART
  
PROSITE
  
PRINTS