CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-042679
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Solute carrier family 12 member 7 
Protein Synonyms/Alias
  
Gene Name
 SLC12A7 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
117LMSTEKTKGFCQLVVubiquitination[1]
295EQRSQMLKQMQLSKNubiquitination[1, 2]
301LKQMQLSKNEQEREAubiquitination[1, 2]
334QAPPTPDKVQMTWTRubiquitination[1, 2, 3, 4]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473]
 [3] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [4] Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization.
 Sarraf SA, Raman M, Guarani-Pereira V, Sowa ME, Huttlin EL, Gygi SP, Harper JW.
 Nature. 2013 Apr 18;496(7445):372-6. [PMID: 23503661
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 347 AA 
Protein Sequence
XVRGWTNPDF LSHRAEKEWG DGIRGLSLNA ARYALLRVEH GPPHTKNWRP QVLVMLNLDA 60
EQAVKHPRLL SFTSQLKAGK GLTIVGSVLE GTYLDKHMEA QRAEENIRSL MSTEKTKGFC 120
QLVVSSSLRD GMSHLIQSAG LGGLKHNTVL MAWPASWKQE DNPFSWKNFV DTVRDTTAAH 180
QALLVAKNVD SFPQNQERFG GGHIDVWWIV HDGGMLMLLP FLLRQHKVWR KCRMRIFTVA 240
QVDDNSIQMK KDLQMFLYHL RISAEVEVVE MVENDISAFT YERTLMMEQR SQMLKQMQLS 300
KNEQEREAQL IHDRNTASHT AAAARTQAPP TPDKVQMTWT REKLIAE 347 
Gene Ontology
  
Interpro
  
Pfam
  
SMART
  
PROSITE
  
PRINTS