UniProt Accession

 GTR12_HUMAN; Q8TD20; B3KV17; Q7Z6U3; Q96MR8 

Genbank Protein ID

 AY046419; AK056554; AK122628; AL035699; AL449363; AL449363; AL035699; CH471051; BC070149 

Genbank Nucleotide ID

 AAL02327.1; BAB71214.1; BAG53629.1; CAD92514.2; CAD92514.2; CAI17977.1; CAI17977.1; EAW47994.1; AAH70149.1 

Protein Name

 Solute carrier family 2, facilitated glucose transporter member 12 

Protein Synonyms/Alias

 Glucose transporter type 12; GLUT-12 

Gene Name

 SLC2A12 

Gene Synonyms/Alias

 GLUT12; GLUT8 

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
235	GQEGAASKVLGRLRA	ubiquitination	[1]
254	TEELTVIKSSLKDEY	ubiquitination	[1, 2, 3]

Reference

 [1] Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass.
 Povlsen LK, Beli P, Wagner SA, Poulsen SL, Sylvestersen KB, Poulsen JW, Nielsen ML, Bekker-Jensen S, Mailand N, Choudhary C.
 Nat Cell Biol. 2012 Oct;14(10):1089-98. [PMID: 23000965]
 [2] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473]
 [3] hCKSAAP_UbSite: improved prediction of human ubiquitination sites by exploiting amino acid pattern and properties.
 Chen Z, Zhou Y, Song J, Zhang Z.
 Biochim Biophys Acta. 2013 Aug;1834(8):1461-7. [PMID: 23603789] 

Functional Description

 Facilitative glucose transporter (By similarity). 

Sequence Annotation

 CARBOHYD 371 371 N-linked (GlcNAc...) (Potential).
 CARBOHYD 383 383 N-linked (GlcNAc...) (Potential).
 CARBOHYD 396 396 N-linked (GlcNAc...) (Potential).
 CARBOHYD 401 401 N-linked (GlcNAc...) (Potential).  

Keyword

 Complete proteome; Cytoplasm; Glycoprotein; Membrane; Reference proteome; Sugar transport; Transmembrane; Transmembrane helix; Transport. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 617 AA 

Protein Sequence

Gene Ontology

 GO:0012505; C:endomembrane system; IEA:UniProtKB-SubCell.
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
 GO:0005886; C:plasma membrane; TAS:Reactome.
 GO:0022891; F:substrate-specific transmembrane transporter activity; IEA:InterPro.
 GO:0008643; P:carbohydrate transport; IEA:UniProtKB-KW.
 GO:0055085; P:transmembrane transport; TAS:Reactome. 

Interpro

 IPR020846; MFS_dom.
 IPR016196; MFS_dom_general_subst_transpt.
 IPR005828; Sub_transporter.
 IPR003663; Sugar/inositol_transpt.
 IPR005829; Sugar_transporter_CS. 

Pfam

 PF00083; Sugar_tr 

SMART

  

PROSITE

 PS50850; MFS
 PS00216; SUGAR_TRANSPORT_1
 PS00217; SUGAR_TRANSPORT_2 

PRINTS

 PR00171; SUGRTRNSPORT.