CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-038958
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Vesicle-fusing ATPase 
Protein Synonyms/Alias
  
Gene Name
 Nsf 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
43VRTSPNHKYIFTLRTacetylation[1]
197SSLNLIGKAKTKENRubiquitination[2]
292NGPEILNKYVGESEAacetylation[1]
303ESEANIRKLFADAEEacetylation[1]
400EIGLPDEKGRLQILHacetylation[1]
461RHIKASTKVEVDMEKubiquitination[2]
468KVEVDMEKAESLQVTubiquitination[2]
528ELLVQQTKNSDRTPLubiquitination[2]
586AKCQAMKKIFDDAYKacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405]
 [2] Synaptic protein ubiquitination in rat brain revealed by antibody-based ubiquitome analysis.
 Na CH, Jones DR, Yang Y, Wang X, Xu Y, Peng J.
 J Proteome Res. 2012 Sep 7;11(9):4722-32. [PMID: 22871113] 
Functional Description
  
Sequence Annotation
  
Keyword
 ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 743 AA 
Protein Sequence
AGETMQAARC PTDELSLSNC AVVNEKDYQS GQHVMVRTSP NHKYIFTLRT HPSVVPGCIA 60
FSLPQRKWAG LSIGQDIEVA LYSFDKAKQC IGTMTIEIDF LQKKNIDSNP YDTDKMAAEF 120
IQQFNNQAFS VGQQLVFSFN DKLFGLLVKD IEAMDPSILK GEPASGKRQK MEIGIQVFHS 180
QVAFEKAENS SLNLIGKAKT KENRQSIINP DWNFEKMGIG GLDKEFSDIF RRAFASRVFP 240
PEIVEQMGCK HVKGILLYGP PGCGKTLLAR QIGKMLNARE PKVVNGPEIL NKYVGESEAN 300
IRKLFADAEE EQRRLGANSG LHIIIFDEID AICKQRGSMA GSTGVHDTVV NQLLSKIDGV 360
EQLNNILVIG MTNRPDLIDE ALLRPGRLEV KMEIGLPDEK GRLQILHIHT ARMRGHQLLS 420
ADVDIKELAV ETKNFSGAEL EGLVRAAQST AMNRHIKAST KVEVDMEKAE SLQVTRGDFL 480
ASLENDIKPA FGTNQEDYAS YIMNGIIKWG DPVTRVLDDG ELLVQQTKNS DRTPLVSVLL 540
EGPPHSGKTA LAAKIAEESN FPFIKICSPD KMIGFSETAK CQAMKKIFDD AYKSQLSCVV 600
VDDIERLLDY VPIGPRFSNL VLQALLVLLK KAPPQGRKLL IIGTTSRKDV LQEMEMLNAF 660
STTIHVPNIA TGEQLLEALE LLGNFKDKER TTIAQQVKGK KVWIGIKKLL MLIEMSLQMD 720
PEYRVRKFLA LMREEGASPL DFD 743 
Gene Ontology
 GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
 GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro. 
Interpro
 IPR003593; AAA+_ATPase.
 IPR009010; Asp_de-COase-like_dom.
 IPR003959; ATPase_AAA_core.
 IPR003960; ATPase_AAA_CS.
 IPR004201; Cdc48_dom2.
 IPR003338; CDC4_N-term_subdom.
 IPR027417; P-loop_NTPase. 
Pfam
 PF00004; AAA
 PF02933; CDC48_2
 PF02359; CDC48_N 
SMART
 SM00382; AAA
 SM01072; CDC48_2
 SM01073; CDC48_N 
PROSITE
 PS00674; AAA 
PRINTS