| Tag | Content |
|---|
| CPLM ID | CPLM-000186 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Synaptotagmin-11 |
Protein Synonyms/Alias | Synaptotagmin XI; SytXI |
Gene Name | Syt11 |
Gene Synonyms/Alias | |
Created Date | July 27, 2013 |
Organism | Rattus norvegicus (Rat) |
NCBI Taxa ID | 10116 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 72 | YPETLSNKKKIIKVR | ubiquitination | [1] |
|
Reference | [1] Synaptic protein ubiquitination in rat brain revealed by antibody-based ubiquitome analysis. Na CH, Jones DR, Yang Y, Wang X, Xu Y, Peng J. J Proteome Res. 2012 Sep 7;11(9):4722-32. [ PMID: 22871113] |
Functional Description | May be involved in Ca(2+)-dependent exocytosis of secretory vesicles through Ca(2+) and phospholipid binding to the C2 domain or may serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis (By similarity). |
Sequence Annotation | DOMAIN 158 261 C2 1.
DOMAIN 292 396 C2 2.
METAL 187 187 Calcium 1 (By similarity).
METAL 187 187 Calcium 2 (By similarity).
METAL 194 194 Calcium 1 (By similarity).
METAL 248 248 Calcium 1; via carbonyl oxygen (By
METAL 249 249 Calcium 1 (By similarity).
METAL 249 249 Calcium 2 (By similarity).
METAL 249 249 Calcium 3 (By similarity).
METAL 252 252 Calcium 3 (By similarity).
METAL 255 255 Calcium 2 (By similarity).
METAL 255 255 Calcium 3 (By similarity). |
Keyword | Calcium; Cell junction; Complete proteome; Cytoplasmic vesicle; Membrane; Metal-binding; Reference proteome; Repeat; Synapse; Transmembrane; Transmembrane helix; Ubl conjugation. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 430 AA |
Protein Sequence | MAEITNIRPS FDVSPVAAGL IGASVLVVCV SVTVFVWTCC HQQAEKKHKT PPYKFIHMLK 60
GISIYPETLS NKKKIIKVRR DKDGSHRESG RGNLLVNAES GLLSHDRDPR GPSPASCIDQ 120
LPIKRDYGEE LRSPMTSLTP GESKPTSPSS PEEDVMLGSL TFSVDYNFPK KALVVTIQEA 180
HGLPVMDGQT QGSDPYIKMT ILPDKRHRVK TRVLRKTLDP VFDETFTFYG IPYSQLQDLV 240
LHFLVLSFDR FSRDDVIGEV MVPLAGVDPS TGKVQLTRDI IKRNIQKCIS RGELQVSLSY 300
QPVAQRMTVV VLKARHLPKM DITGLSGNPY VKVNVYYGRK RIAKKKTHVK KCTLNPIFNE 360
SFIYDIPTDL LPDISIEFLV IDFDRTTKNE VVGRLILGAH SVTTSGAEHW REVCESPRKP 420
VAKWHSLSEY 430 |
Gene Ontology | GO:0030054; C:cell junction; IEA:UniProtKB-KW. GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. GO:0008021; C:synaptic vesicle; TAS:RGD. GO:0030672; C:synaptic vesicle membrane; IEA:UniProtKB-SubCell. GO:0005509; F:calcium ion binding; IDA:RGD. GO:0005544; F:calcium-dependent phospholipid binding; IDA:RGD. GO:0005215; F:transporter activity; IEA:InterPro. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |