CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-018244
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Conserved oligomeric Golgi complex subunit 1 
Protein Synonyms/Alias
 COG complex subunit 1; Component of oligomeric Golgi complex 1 
Gene Name
 COG1 
Gene Synonyms/Alias
 KIAA1381; LDLB 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
11AATSPALKRLDLRDPubiquitination[1, 2]
45RAEIEHKKEELRQMVubiquitination[2]
81VGLVDAVKATDQYCAubiquitination[2]
431DRLQTLTKEGFDSISubiquitination[3]
524FCSALDSKLKVKLDDubiquitination[2]
526SALDSKLKVKLDDLLubiquitination[2]
528LDSKLKVKLDDLLAYubiquitination[3]
553DVSPTQAKSSAFDRYubiquitination[3]
607QDALNSAKLHSVLFMubiquitination[2]
666EIIPTQAKWQEVKEVubiquitination[3]
Reference
 [1] Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition.
 Udeshi ND, Mani DR, Eisenhaure T, Mertins P, Jaffe JD, Clauser KR, Hacohen N, Carr SA.
 Mol Cell Proteomics. 2012 May;11(5):148-59. [PMID: 22505724]
 [2] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [3] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983] 
Functional Description
 Required for normal Golgi function (By similarity). 
Sequence Annotation
 MOD_RES 2 2 N-acetylalanine.  
Keyword
 Acetylation; Complete proteome; Congenital disorder of glycosylation; Golgi apparatus; Membrane; Polymorphism; Protein transport; Reference proteome; Transport. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 980 AA 
Protein Sequence
MATAATSPAL KRLDLRDPAA LFETHGAEEI RGLERQVRAE IEHKKEELRQ MVGERYRDLI 60
EAADTIGQMR RCAVGLVDAV KATDQYCARL RQAGSAAPRP PRAQQPQQPS QEKFYSMAAQ 120
IKLLLEIPEK IWSSMEASQC LHATQLYLLC CHLHSLLQLD SSSSRYSPVL SRFPILIRQV 180
AAASHFRSTI LHESKMLLKC QGVSDQAVAE ALCSIMLLEE SSPRQALTDF LLARKATIQK 240
LLNQPHHGAG IKAQICSLVE LLATTLKQAH ALFYTLPEGL LPDPALPCGL LFSTLETITG 300
QHPAGKGTGV LQEEMKLCSW FKHLPASIVE FQPTLRTLAH PISQEYLKDT LQKWIHMCNE 360
DIKNGITNLL MYVKSMKGLA GIRDAMWELL TNESTNHSWD VLCRRLLEKP LLFWEDMMQQ 420
LFLDRLQTLT KEGFDSISSS SKELLVSALQ ELESSTSNSP SNKHIHFEYN MSLFLWSESP 480
NDLPSDAAWV SVANRGQFAS SGLSMKAQAI SPCVQNFCSA LDSKLKVKLD DLLAYLPSDD 540
SSLPKDVSPT QAKSSAFDRY ADAGTVQEML RTQSVACIKH IVDCIRAELQ SIEEGVQGQQ 600
DALNSAKLHS VLFMARLCQS LGELCPHLKQ CILGKSESSE KPAREFRALR KQGKVKTQEI 660
IPTQAKWQEV KEVLLQQSVM GYQVWSSAVV KVLIHGFTQS LLLDDAGSVL ATATSWDELE 720
IQEEAESGSS VTSKIRLPAQ PSWYVQSFLF SLCQEINRVG GHALPKVTLQ EMLKSCMVQV 780
VAAYEKLSEE KQIKKEGAFP VTQNRALQLL YDLRYLNIVL TAKGDEVKSG RSKPDSRIEK 840
VTDHLEALID PFDLDVFTPH LNSNLHRLVQ RTSVLFGLVT GTENQLAPRS STFNSQEPHN 900
ILPLASSQIR FGLLPLSMTS TRKAKSTRNI ETKAQVVPPA RSTAGDPTVP GSLFRQLVSE 960
EDNTSAPSLF KLGWLSSMTK 980 
Gene Ontology
 GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
 GO:0017119; C:Golgi transport complex; IDA:UniProtKB.
 GO:0007030; P:Golgi organization; NAS:UniProtKB.
 GO:0006891; P:intra-Golgi vesicle-mediated transport; NAS:UniProtKB.
 GO:0015031; P:protein transport; IEA:UniProtKB-KW. 
Interpro
 IPR014812; Vps51. 
Pfam
 PF08700; Vps51 
SMART
  
PROSITE
  
PRINTS