| Tag | Content |
|---|
| CPLM ID | CPLM-007372 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Ran-specific GTPase-activating protein 2 |
Protein Synonyms/Alias | Ran-binding protein 2; RANBP2 |
Gene Name | YRB2 |
Gene Synonyms/Alias | YIL063C |
Created Date | July 27, 2013 |
Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) |
NCBI Taxa ID | 559292 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 27 | AVENPIDKLDGTPKR | acetylation | [1] |
|
Reference | [1] Proteome-wide analysis of lysine acetylation suggests its broad regulatory scope in Saccharomyces cerevisiae. Henriksen P, Wagner SA, Weinert BT, Sharma S, Bacinskaja G, Rehman M, Juffer AH, Walther TC, Lisby M, Choudhary C. Mol Cell Proteomics. 2012 Nov;11(11):1510-22. [ PMID: 22865919] |
Functional Description | Important for the export of protein containing nuclear export signal (NES) out of the nucleus. Stimulates the GTPase activity of GSP1. |
Sequence Annotation | DOMAIN 191 327 RanBD1.
MOD_RES 31 31 Phosphothreonine.
MOD_RES 179 179 Phosphoserine. |
Keyword | Complete proteome; GTPase activation; Nucleus; Phosphoprotein; Protein transport; Reference proteome; Transport. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 327 AA |
Protein Sequence | MSETNGGNAA RENSEVKQTA VENPIDKLDG TPKRPREKDQ DEQAEETSDK SEAPNKNDEE 60
KKEEGKKDQE PSHKKIKVDD GKTVESGIVE DDKKEDKFVF GAASKFGTGF GVAKKDTKDG 120
DATTSTESLP ASDSKTKKPF AFGSGLSFGS GFNILKNKTE NNSESEKKAT DVDKDKVHSG 180
SEQLANASED TKDKPKPLKL QKQEVKSGEE SEECIYQVNA KLYQLSNIKE GWKERGVGII 240
KINKSKDDVE KTRIVMRSRG ILKVILNIQL VKGFTVQKGF TGSLQSEKFI RLLAVDDNGD 300
PAQYAIKTGK KETTDELYNI IVKSVPK 327 |
Gene Ontology | GO:0005829; C:cytosol; IDA:SGD. GO:0005643; C:nuclear pore; IDA:SGD. GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW. GO:0043547; P:positive regulation of GTPase activity; IEA:GOC. GO:0006611; P:protein export from nucleus; IMP:SGD. GO:0031938; P:regulation of chromatin silencing at telomere; IMP:SGD. GO:0000056; P:ribosomal small subunit export from nucleus; IMP:SGD. |
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Pfam | |
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PRINTS | |