Tag | Content |
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CPLM ID | CPLM-003854 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Cytochrome c oxidase subunit 4 isoform 1, mitochondrial |
Protein Synonyms/Alias | Cytochrome c oxidase polypeptide IV; Cytochrome c oxidase subunit IV isoform 1; COX IV-1 |
Gene Name | Cox4i1 |
Gene Synonyms/Alias | Cox4; Cox4a |
Created Date | July 27, 2013 |
Organism | Rattus norvegicus (Rat) |
NCBI Taxa ID | 10116 |
Lysine Modification | Position | Peptide | Type | References |
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29 | RAHGSVVKSEDYALP | acetylation | [1] | 53 | LPDVAHVKLLSASQK | acetylation | [1] | 60 | KLLSASQKALKEKEK | acetylation | [1] | 65 | SQKALKEKEKADWSS | acetylation | [1] | 67 | KALKEKEKADWSSLS | acetylation | [1] | 78 | SSLSRDEKVQLYRIQ | acetylation | [1] | 95 | ESFAEMNKGTNEWKT | acetylation | [1] | 149 | TKRMLDMKVNPIQGF | acetylation | [1] | 159 | PIQGFSAKWDYNKNE | acetylation | [1] | 164 | SAKWDYNKNEWKK** | acetylation | [1] | 168 | DYNKNEWKK****** | acetylation | [1] |
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Reference | [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns. Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV. Cell Rep. 2012 Aug 30;2(2):419-31. [ PMID: 22902405] |
Functional Description | This protein is one of the nuclear-coded polypeptide chains of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport. |
Sequence Annotation | MOD_RES 53 53 N6-acetyllysine (By similarity). MOD_RES 60 60 N6-acetyllysine (By similarity). |
Keyword | Acetylation; Complete proteome; Direct protein sequencing; Membrane; Mitochondrion; Mitochondrion inner membrane; Reference proteome; Transit peptide. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 169 AA |
Protein Sequence | MLATRALSLI GKRAISTSVC LRAHGSVVKS EDYALPSYVD RRDYPLPDVA HVKLLSASQK 60 ALKEKEKADW SSLSRDEKVQ LYRIQFNESF AEMNKGTNEW KTVVGLAMFF IGFTALVLIW 120 EKSYVYGPIP HTFDRDWVAM QTKRMLDMKV NPIQGFSAKW DYNKNEWKK 169 |
Gene Ontology | GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell. GO:0005634; C:nucleus; IEA:Compara. GO:0004129; F:cytochrome-c oxidase activity; IEA:InterPro. GO:0007584; P:response to nutrient; IEP:RGD. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |