CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-010990
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 ADP-ribosylation factor-like protein 3 
Protein Synonyms/Alias
 Arf-like GTPase 3 
Gene Name
 ARL3 
Gene Synonyms/Alias
 ARP1; YPL051W 
Created Date
 July 27, 2013 
Organism
 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 
NCBI Taxa ID
 559292 
Lysine Modification
Position
Peptide
Type
References
50LAFKALEKIQPTVGQubiquitination[1, 2]
Reference
 [1] Sites of ubiquitin attachment in Saccharomyces cerevisiae.
 Starita LM, Lo RS, Eng JK, von Haller PD, Fields S.
 Proteomics. 2012 Jan;12(2):236-40. [PMID: 22106047]
 [2] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.
 Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, VillĂ©n J.
 Nat Methods. 2013 Jul;10(7):676-82. [PMID: 23749301
Functional Description
 Involved in the targeting of ARL1 to the Golgi. Can bind and hydrolyze GTP. 
Sequence Annotation
 NP_BIND 24 31 GTP (By similarity).
 NP_BIND 74 78 GTP (By similarity).
 NP_BIND 133 136 GTP (By similarity).
 MOD_RES 1 1 N-acetylmethionine.  
Keyword
 Acetylation; Complete proteome; Golgi apparatus; GTP-binding; Nucleotide-binding; Protein transport; Reference proteome; Transport. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 198 AA 
Protein Sequence
MFHLVKGLYN NWNKKEQYSI LILGLDNAGK TTFLETLKKE YSLAFKALEK IQPTVGQNVA 60
TIPVDSKQIL KFWDVGGQES LRSMWSEYYS LCHGIIFIVD SSDRERLDEC STTLQSVVMD 120
EEIEGVPILM LANKQDRQDR MEVQDIKEVF NKIAEHISAR DSRVLPISAL TGEGVKDAIE 180
WMIVRLERNK KSRPPIYK 198 
Gene Ontology
 GO:0005794; C:Golgi apparatus; IDA:SGD.
 GO:0042175; C:nuclear outer membrane-endoplasmic reticulum membrane network; IDA:SGD.
 GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
 GO:0003924; F:GTPase activity; IDA:SGD.
 GO:0043001; P:Golgi to plasma membrane protein transport; IMP:SGD.
 GO:0033365; P:protein localization to organelle; IMP:SGD.
 GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. 
Interpro
 IPR027417; P-loop_NTPase.
 IPR005225; Small_GTP-bd_dom.
 IPR024156; Small_GTPase_ARF.
 IPR006689; Small_GTPase_ARF/SAR. 
Pfam
 PF00025; Arf 
SMART
 SM00177; ARF 
PROSITE
 PS51417; ARF 
PRINTS
 PR00328; SAR1GTPBP.