CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-019138
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 60S ribosomal export protein NMD3 
Protein Synonyms/Alias
 hNMD3 
Gene Name
 NMD3 
Gene Synonyms/Alias
 CGI-07 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
150DCHRVEAKDFWKAVIubiquitination[1]
Reference
 [1] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473
Functional Description
 Acts as an adapter for the XPO1/CRM1-mediated export of the 60S ribosomal subunit. 
Sequence Annotation
 REGION 425 503 Necessary for the nuclear export of the
 MOTIF 405 422 Nuclear and nucleolar localization
 MOTIF 480 489 Nuclear export signal.
 MOD_RES 1 1 N-acetylmethionine.
 MOD_RES 433 433 Phosphothreonine.
 MOD_RES 468 468 Phosphoserine.
 MOD_RES 470 470 Phosphothreonine.  
Keyword
 Acetylation; Complete proteome; Cytoplasm; Nucleus; Phosphoprotein; Polymorphism; Protein transport; Reference proteome; Transport. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 503 AA 
Protein Sequence
MEYMAESTDR SPGHILCCEC GVPISPNPAN ICVACLRSKV DISQGIPKQV SISFCKQCQR 60
YFQPPGTWIQ CALESRELLA LCLKKIKAPL SKVRLVDAGF VWTEPHSKRL KVKLTIQKEV 120
MNGAILQQVF VVDYVVQSQM CGDCHRVEAK DFWKAVIQVR QKTLHKKTFY YLEQLILKYG 180
MHQNTLRIKE IHDGLDFYYS SKQHAQKMVE FLQCTVPCRY KASQRLISQD IHSNTYNYKS 240
TFSVEIVPIC KDNVVCLSPK LAQSLGNMNQ ICVCIRVTSA IHLIDPNTLQ VADIDGSTFW 300
SHPFNSLCHP KQLEEFIVME CSIVQDIKRA AGAGMISKKH TLGEVWVQKT SEMNTDKQYF 360
CRTHLGHLLN PGDLVLGFDL ANCNLNDEHV NKMNSDRVPD VVLIKKSYDR TKRQRRRNWK 420
LKELAREREN MDTDDERQYQ DFLEDLEEDE AIRKNVNIYR DSAIPVESDT DDEGAPRISL 480
AEMLEDLHIS QDATGEEGAS MLT 503 
Gene Ontology
 GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
 GO:0005730; C:nucleolus; IDA:HPA.
 GO:0005654; C:nucleoplasm; IEA:UniProtKB-SubCell.
 GO:0015031; P:protein transport; IEA:UniProtKB-KW. 
Interpro
 IPR007064; NMD3. 
Pfam
 PF04981; NMD3 
SMART
  
PROSITE
  
PRINTS