Tag | Content |
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CPLM ID | CPLM-015537 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | UDP-glucuronosyltransferase 1-7C |
Protein Synonyms/Alias | UDPGT 1-7C; UGT1*7C; UGT1-07C; UGT1.7C; UDP-glucuronosyltransferase 1A7C; UGT1A10 |
Gene Name | Ugt1a7c |
Gene Synonyms/Alias | Ugt1a10 |
Created Date | July 27, 2013 |
Organism | Mus musculus (Mouse) |
NCBI Taxa ID | 10090 |
Lysine Modification | Position | Peptide | Type | References |
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316 | VSEIPEKKAMEIAEA | ubiquitination | [1] | 345 | TRPSNLAKNTILVKW | ubiquitination | [1] | 351 | AKNTILVKWLPQNDL | ubiquitination | [1] | 363 | NDLLGHPKTRAFITH | ubiquitination | [1] | 432 | LKTVINNKSYKENIM | ubiquitination | [1] | 435 | VINNKSYKENIMRLS | ubiquitination | [1] |
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Reference | [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues. Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C. Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [ PMID: 22790023] |
Functional Description | UDPGT is of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. This isoform has specificity for phenols. |
Sequence Annotation | CARBOHYD 293 293 N-linked (GlcNAc...) (Potential). CARBOHYD 431 431 N-linked (GlcNAc...) (Potential). |
Keyword | Alternative splicing; Complete proteome; Endoplasmic reticulum; Glycoprotein; Glycosyltransferase; Membrane; Microsome; Reference proteome; Signal; Transferase; Transmembrane; Transmembrane helix. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 531 AA |
Protein Sequence | MAPADFPASL PLCVCLLLAS GLAQAGRLLV VPMDGSHWFT MQTVVEKLLH KGHEVVVVVP 60 EVSWQLTKPL NFVVKTYAVS HTQEDLNREF KIFIDAQWKS QQEGGILPLL DSPAKGFFEL 120 LFSHCRSLFN DKKLVEYLKQ TSFDAVFLDP FDVCGLTVAK YFSLPSVVFS RGIFCHYLED 180 AAQCPSPPSY IPRMLLKFTD TMTFKERTRN LLAYMGERAF CHKFFKSAAD IASEVLQTPV 240 TMTDLFSPVS IWLLRTDFVL EFPRPVMPNV IYIGGINCHQ GKPLSKEFEA YVNASGEHGI 300 VVFSLGSMVS EIPEKKAMEI AEALGRIPQT VLWRYTGTRP SNLAKNTILV KWLPQNDLLG 360 HPKTRAFITH SGSHGIYEGI CNGVPMVMMP LFGDQMDNAK RMETRGAGVT LNVLEMTADD 420 LENALKTVIN NKSYKENIMR LSSLHKDRPI EPLDLAVFWV EYVMRHKGAP HLRPAAHDLT 480 WYQYHSLDVI GFLLAIVLTV VFIVFKCCAY GCRKCFGGKG RVKKSHKSKT H 531 |
Gene Ontology | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell. GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. GO:0015020; F:glucuronosyltransferase activity; IEA:EC. |
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