UniProt Accession

 G5E952_HUMAN; G5E952 

Genbank Protein ID

 AP001062; CH471079 

Genbank Nucleotide ID

 EAX09433.1 

Protein Name

 Chromosome 21 open reading frame 2, isoform CRA_c 

Protein Synonyms/Alias

 Protein C21orf2 

Gene Name

 C21orf2 

Gene Synonyms/Alias

 hCG_401309 

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
22	SELHSVRKLNCWGSR	ubiquitination	[1]
84	LAELFYLKGLPRLRV	ubiquitination	[1]
120	RTLPRLQKLDNQAVT	ubiquitination	[1, 2]

Reference

 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Leucine-rich repeat; Reference proteome; Repeat. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 255 AA 

Protein Sequence

Gene Ontology

  

Interpro

 IPR001611; Leu-rich_rpt.
 IPR025875; Leu-rich_rpt_4.
 IPR003603; U2A'_phosphoprotein32A_C. 

Pfam

 PF12799; LRR_4 

SMART

 SM00446; LRRcap 

PROSITE

 PS51450; LRR 

PRINTS