CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-014031
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Intermediate filament family orphan 2 
Protein Synonyms/Alias
  
Gene Name
 IFFO2 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
58GSNIHLLKGLNVRFRubiquitination[1]
70RFRCFLAKVHELERRubiquitination[2]
83RRNRLLEKQLEQQQSubiquitination[1, 2, 3]
99RERRLRYKTFSREQAubiquitination[2]
211ALYNVLAKVKRERDEubiquitination[2]
213YNVLAKVKRERDEYKubiquitination[2]
303RRIDITAKLCDVAQQubiquitination[2]
318RNSEDVSKIFQVVPKubiquitination[1, 2]
325KIFQVVPKKKERKVAubiquitination[2]
330VPKKKERKVASDDDIubiquitination[1]
446ELELATAKSDMNRHLubiquitination[1, 2]
463YMEMCSMKRGLDVQMubiquitination[2]
Reference
 [1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [2] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [3] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 517 AA 
Protein Sequence
MVNSLLFGEM ALAFGCPPGG GGGGCPGGGG GGGGAGPGPS PVTAALRDDL GSNIHLLKGL 60
NVRFRCFLAK VHELERRNRL LEKQLEQQQS ERERRLRYKT FSREQAVQTG PELLRPPAPG 120
GGHGLSSGAA AGANANAVAL GGLPPGGGSH PQHYGRLPGT IWSYTQVRRT GGGGVETVQG 180
PGVSWVHPDG VGVQIDTITP EIRALYNVLA KVKRERDEYK RRWEEELAKR MNLQTMVDTL 240
QEAAQEADAI QEEMNEKIER LKAELVVFKG LMSDPMTDLD TKIQEKAMKV DMDICRRIDI 300
TAKLCDVAQQ RNSEDVSKIF QVVPKKKERK VASDDDISEQ DGEVNRFSDD EVGSMNITDE 360
MKRMFNQLRE TFDFDDDCDS LTWEENEDTL LLWEDFTNCN PTIDLQGEQE ENLGNLIHET 420
ESFFKTRDKE YQETIGQIEL ELATAKSDMN RHLHEYMEMC SMKRGLDVQM ETCRRLIKGS 480
ADRNSPSPSS VASSDSGSTD EIQDEFEREA DVEPMVS 517 
Gene Ontology
  
Interpro
 IPR016044; F.
 IPR026665; Iffo1/2. 
Pfam
 PF00038; Filament 
SMART
  
PROSITE
  
PRINTS