| Tag | Content |
|---|
| CPLM ID | CPLM-024132 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Peptidyl-prolyl cis-trans isomerase FKBP9 |
Protein Synonyms/Alias | PPIase FKBP9; 63 kDa FK506-binding protein; 63 kDa FKBP; FKBP-63; FK506-binding protein 9; FKBP-9; FKBP65RS; Rotamase |
Gene Name | Fkbp9 |
Gene Synonyms/Alias | Fkbp60; Fkbp63 |
Created Date | July 27, 2013 |
Organism | Mus musculus (Mouse) |
NCBI Taxa ID | 10090 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 70 | GTFLDGQKFDSSYDR | acetylation | [1] | | 539 | FNAEMIVKNMFTNQD | acetylation | [1] |
|
Reference | [1] Quantitative acetylome analysis reveals the roles of SIRT1 in regulating diverse substrates and cellular pathways. Chen Y, Zhao W, Yang JS, Cheng Z, Luo H, Lu Z, Tan M, Gu W, Zhao Y. Mol Cell Proteomics. 2012 Oct;11(10):1048-62. [ PMID: 22826441] |
Functional Description | PPIases accelerate the folding of proteins during protein synthesis. |
Sequence Annotation | DOMAIN 54 142 PPIase FKBP-type 1.
DOMAIN 166 254 PPIase FKBP-type 2.
DOMAIN 278 365 PPIase FKBP-type 3.
DOMAIN 389 477 PPIase FKBP-type 4.
DOMAIN 488 523 EF-hand 1.
DOMAIN 533 568 EF-hand 2.
MOTIF 567 570 Prevents secretion from ER (Potential).
CARBOHYD 174 174 N-linked (GlcNAc...).
CARBOHYD 286 286 N-linked (GlcNAc...) (Potential).
CARBOHYD 302 302 N-linked (GlcNAc...) (Potential).
CARBOHYD 397 397 N-linked (GlcNAc...) (Potential). |
Keyword | Calcium; Complete proteome; Endoplasmic reticulum; Glycoprotein; Isomerase; Metal-binding; Phosphoprotein; Reference proteome; Repeat; Rotamase; Signal. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 570 AA |
Protein Sequence | MALGARGWRR RSLLLLLLWV TGQAAPVLGL AVSSELQIQQ SFVPDECPRT VHSGDFVRYH 60
YVGTFLDGQK FDSSYDRDST FNVFVGKGQL IAGMDQALVG MCVNERRLVT IPPNLAYGSE 120
GVSGVIPPNS VLHFDVLLVD IWNSEDQVHI QTYFKPPSCP RTIQVSDFVR YHYNGTFLDG 180
TLFDSSHNRM KTYDTYVGIG WLIPGMDKGL LGMCVGEKRI ITVPPFLAYG EEGDGKDIPG 240
QASLVFDVAL LDLHNPKDTI SIENKVVPEN CERRSQSGDF LRYHYNGTLL DGTLFDSSYS 300
RNHTFDTYIG QGYVIPGMDE GLLGVCIGER RRIVVPPHLG YGEKGRGSIP GSAVLVFDIH 360
VIDFHNPSDS ISITSHYKPP DCSVLSKKGD YLKYHYNASL LDGTLLDSTW NLGKTYNIVL 420
GSGQVVLGMD MGLREMCVGE KRTVIIPPHL GYGEAGVDGE VPGSAVLVFD IELLELVSGL 480
PEGYMFIWNG EVSPNLFEEI DRDGNGEVLL EEFSEYIHAQ VATGKGKLAP GFNAEMIVKN 540
MFTNQDRNGD GKVTAEEFKL KDQEAKHDEL 570 |
Gene Ontology | GO:0005783; C:endoplasmic reticulum; IDA:UniProtKB. GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell. GO:0016020; C:membrane; IBA:RefGenome. GO:0005509; F:calcium ion binding; IDA:UniProtKB. GO:0005528; F:FK506 binding; IBA:RefGenome. GO:0003755; F:peptidyl-prolyl cis-trans isomerase activity; IBA:RefGenome. GO:0006457; P:protein folding; IDA:UniProtKB. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |