CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-006974
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Probable glucose transporter HXT5 
Protein Synonyms/Alias
  
Gene Name
 HXT5 
Gene Synonyms/Alias
 YHR096C 
Created Date
 July 27, 2013 
Organism
 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 
NCBI Taxa ID
 559292 
Lysine Modification
Position
Peptide
Type
References
61ISHEGPPKDELEELQubiquitination[1, 2, 3]
Reference
 [1] A proteomics approach to understanding protein ubiquitination.
 Peng J, Schwartz D, Elias JE, Thoreen CC, Cheng D, Marsischky G, Roelofs J, Finley D, Gygi SP.
 Nat Biotechnol. 2003 Aug;21(8):921-6. [PMID: 12872131]
 [2] Computational identification of ubiquitylation sites from protein sequences.
 Tung CW, Ho SY.
 BMC Bioinformatics. 2008 Jul 15;9:310. [PMID: 18625080]
 [3] Identification, analysis, and prediction of protein ubiquitination sites.
 Radivojac P, Vacic V, Haynes C, Cocklin RR, Mohan A, Heyen JW, Goebl MG, Iakoucheva LM.
 Proteins. 2010 Feb 1;78(2):365-80. [PMID: 19722269] 
Functional Description
 Probable glucose transporter. 
Sequence Annotation
 CARBOHYD 126 126 N-linked (GlcNAc...) (Potential).
 CARBOHYD 249 249 N-linked (GlcNAc...) (Potential).
 CROSSLNK 61 61 Glycyl lysine isopeptide (Lys-Gly)  
Keyword
 Complete proteome; Glycoprotein; Isopeptide bond; Membrane; Reference proteome; Repeat; Sugar transport; Transmembrane; Transmembrane helix; Transport; Ubl conjugation. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 592 AA 
Protein Sequence
MSELENAHQG PLEGSATVST NSNSYNEKSG NSTAPGTAGY NDNLAQAKPV SSYISHEGPP 60
KDELEELQKE VDKQLEKKSK SDLLFVSVCC LMVAFGGFVF GWDTGTISGF VRQTDFIRRF 120
GSTRANGTTY LSDVRTGLMV SIFNIGCAIG GIVLSKLGDM YGRKIGLMTV VVIYSIGIII 180
QIASIDKWYQ YFIGRIISGL GVGGITVLAP MLISEVSPKQ LRGTLVSCYQ LMITFGIFLG 240
YCTNFGTKNY SNSVQWRVPL GLCFAWSIFM IVGMTFVPES PRYLVEVGKI EEAKRSLARA 300
NKTTEDSPLV TLEMENYQSS IEAERLAGSA SWGELVTGKP QMFRRTLMGM MIQSLQQLTG 360
DNYFFYYGTT IFQAVGLEDS FETAIVLGVV NFVSTFFSLY TVDRFGRRNC LLWGCVGMIC 420
CYVVYASVGV TRLWPNGQDQ PSSKGAGNCM IVFACFYIFC FATTWAPVAY VLISESYPLR 480
VRGKAMSIAS ACNWIWGFLI SFFTPFITSA INFYYGYVFM GCMVFAYFYV FFFVPETKGL 540
TLEEVNEMYE ENVLPWKSTK WIPPSRRTTD YDLDATRNDP RPFYKRMFTK EK 592 
Gene Ontology
 GO:0016021; C:integral to membrane; ISM:SGD.
 GO:0005886; C:plasma membrane; IDA:SGD.
 GO:0005353; F:fructose transmembrane transporter activity; IGI:SGD.
 GO:0005355; F:glucose transmembrane transporter activity; IDA:SGD.
 GO:0015578; F:mannose transmembrane transporter activity; IGI:SGD. 
Interpro
 IPR020846; MFS_dom.
 IPR016196; MFS_dom_general_subst_transpt.
 IPR005828; Sub_transporter.
 IPR003663; Sugar/inositol_transpt.
 IPR005829; Sugar_transporter_CS. 
Pfam
 PF00083; Sugar_tr 
SMART
  
PROSITE
 PS50850; MFS
 PS00216; SUGAR_TRANSPORT_1
 PS00217; SUGAR_TRANSPORT_2 
PRINTS
 PR00171; SUGRTRNSPORT.