UniProt Accession

 LRP1_MOUSE; Q91ZX7; Q61291; Q920Y4 

Genbank Protein ID

 X67469; AF367720; AF369477; AF369389; AF369390; AF369391; AF369392; AF369393; AF369394; AF369395; AF369396; AF369397; AF369398; AF369399; AF369400; AF369401; AF369402; AF369403; AF369404; AF369405; AF369406; AF369407; AF369408; AF369409; AF369410; AF369411; AF369412; AF369413; AF369414; AF369415; AF369416; AF369417; AF369418; AF369419; AF369420; AF369421; AF369422; AF369423; AF369424; AF369425; AF369426; AF369427; AF369428; AF369429; AF369430; AF369431; AF369432; AF369433; AF369434; AF369435; AF369436; AF369437; AF369438; AF369439; AF369440; AF369441; AF369442; AF369443; AF369444; AF369445; AF369446; AF369447; AF369448; AF369449; AF369450; AF369451; AF369452; AF369453; AF369454; AF369455; AF369456; AF369457; AF369458; AF369459; AF369460; AF369461; AF369462; AF369463; AF369464; AF369465; AF369466; AF369467; AF369468; AF369469; AF369470; AF369471; AF369472; AF369473; AF369474; AF369475; AF369476 

Genbank Nucleotide ID

 CAA47817.1; AAL09566.1; AAL09567.1; AAL09567.1; AAL09567.1; AAL09567.1; AAL09567.1; AAL09567.1; AAL09567.1; AAL09567.1; AAL09567.1; AAL09567.1; AAL09567.1; AAL09567.1; AAL09567.1; AAL09567.1; AAL09567.1; AAL09567.1; AAL09567.1; AAL09567.1; AAL09567.1; AAL09567.1; AAL09567.1; AAL09567.1; AAL09567.1; AAL09567.1; AAL09567.1; AAL09567.1; AAL09567.1; AAL09567.1; AAL09567.1; AAL09567.1; AAL09567.1; AAL09567.1; AAL09567.1; AAL09567.1; AAL09567.1; AAL09567.1; AAL09567.1; AAL09567.1; AAL09567.1; AAL09567.1; AAL09567.1; AAL09567.1; AAL09567.1; AAL09567.1; AAL09567.1; AAL09567.1; AAL09567.1; AAL09567.1; AAL09567.1; AAL09567.1; AAL09567.1; AAL09567.1; AAL09567.1; AAL09567.1; AAL09567.1; AAL09567.1; AAL09567.1; AAL09567.1; AAL09567.1; AAL09567.1; AAL09567.1; AAL09567.1; AAL09567.1; AAL09567.1; AAL09567.1; AAL09567.1; AAL09567.1; AAL09567.1; AAL09567.1; AAL09567.1; AAL09567.1; AAL09567.1; AAL09567.1; AAL09567.1; AAL09567.1; AAL09567.1; AAL09567.1; AAL09567.1; AAL09567.1; AAL09567.1; AAL09567.1; AAL09567.1; AAL09567.1; AAL09567.1; AAL09567.1; AAL09567.1; AAL09567.1; AAL09567.1; AAL09567.1 

Protein Name

 Prolow-density lipoprotein receptor-related protein 1 

Protein Synonyms/Alias

 LRP-1; Alpha-2-macroglobulin receptor; A2MR; CD91; Low-density lipoprotein receptor-related protein 1 85 kDa subunit; LRP-85; Low-density lipoprotein receptor-related protein 1 515 kDa subunit; LRP-515; Low-density lipoprotein receptor-related protein 1 intracellular domain; LRPICD 

Gene Name

 Lrp1 

Gene Synonyms/Alias

 A2mr 

Created Date

 July 27, 2013 

Organism

 Mus musculus (Mouse) 

NCBI Taxa ID

 10090 

Lysine Modification

Position	Peptide	Type	References
1110	HVCDPNVKFGCKDSA	acetylation	[1]
1287	IRRIDLHKGDYSVLV	ubiquitination	[2]
2010	VISQGLDKPRAITVH	acetylation	[3]

Reference

 [1] Quantitative acetylome analysis reveals the roles of SIRT1 in regulating diverse substrates and cellular pathways.
 Chen Y, Zhao W, Yang JS, Cheng Z, Luo H, Lu Z, Tan M, Gu W, Zhao Y.
 Mol Cell Proteomics. 2012 Oct;11(10):1048-62. [PMID: 22826441]
 [2] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023]
 [3] SIRT5-Mediated Lysine Desuccinylation Impacts Diverse Metabolic Pathways.
 Park J, Chen Y, Tishkoff DX, Peng C, Tan M, Dai L, Xie Z, Zhang Y, Zwaans BM, Skinner ME, Lombard DB, Zhao Y.
 Mol Cell. 2013 Jun 27;50(6):919-30. [PMID: 23806337] 

Functional Description

 Endocytic receptor involved in endocytosis and in phagocytosis of apoptotic cells. Required for early embryonic development. Involved in cellular lipid homeostasis. Involved in the plasma clearance of chylomicron remnants and activated LRPAP1 (alpha 2-macroglobulin), as well as the local metabolism of complexes between plasminogen activators and their endogenous inhibitors. May modulate cellular events, such as APP metabolism, kinase-dependent intracellular signaling, neuronal calcium signaling as well as neurotransmission. 

Sequence Annotation

 DOMAIN 26 67 LDL-receptor class A 1.
 DOMAIN 71 111 LDL-receptor class A 2.
 DOMAIN 112 150 EGF-like 1.
 DOMAIN 151 190 EGF-like 2; calcium-binding (Potential).
 REPEAT 293 335 LDL-receptor class B 1.
 REPEAT 336 379 LDL-receptor class B 2.
 REPEAT 380 423 LDL-receptor class B 3.
 DOMAIN 475 521 EGF-like 3.
 REPEAT 572 614 LDL-receptor class B 4.
 REPEAT 615 660 LDL-receptor class B 5.
 REPEAT 661 711 LDL-receptor class B 6.
 REPEAT 712 755 LDL-receptor class B 7.
 DOMAIN 804 844 EGF-like 4.
 DOMAIN 853 893 LDL-receptor class A 3.
 DOMAIN 894 934 LDL-receptor class A 4.
 DOMAIN 935 974 LDL-receptor class A 5.
 DOMAIN 975 1014 LDL-receptor class A 6.
 DOMAIN 1014 1054 LDL-receptor class A 7.
 DOMAIN 1061 1100 LDL-receptor class A 8.
 DOMAIN 1103 1143 LDL-receptor class A 9.
 DOMAIN 1144 1183 LDL-receptor class A 10.
 DOMAIN 1184 1223 EGF-like 5.
 DOMAIN 1224 1263 EGF-like 6.
 REPEAT 1310 1356 LDL-receptor class B 8.
 REPEAT 1357 1399 LDL-receptor class B 9.
 REPEAT 1400 1446 LDL-receptor class B 10.
 REPEAT 1447 1491 LDL-receptor class B 11.
 REPEAT 1492 1532 LDL-receptor class B 12.
 DOMAIN 1537 1580 EGF-like 7.
 REPEAT 1628 1670 LDL-receptor class B 13.
 REPEAT 1671 1714 LDL-receptor class B 14.
 REPEAT 1715 1754 LDL-receptor class B 15.
 REPEAT 1755 1799 LDL-receptor class B 16.
 DOMAIN 1847 1888 EGF-like 8.
 REPEAT 1935 1977 LDL-receptor class B 17.
 REPEAT 1978 2020 LDL-receptor class B 18.
 REPEAT 2021 2064 LDL-receptor class B 19.
 REPEAT 2065 2108 LDL-receptor class B 20.
 DOMAIN 2156 2196 EGF-like 9.
 REPEAT 2254 2295 LDL-receptor class B 21.
 REPEAT 2296 2344 LDL-receptor class B 22.
 REPEAT 2345 2389 LDL-receptor class B 23.
 REPEAT 2390 2432 LDL-receptor class B 24.
 REPEAT 2433 2474 LDL-receptor class B 25.
 DOMAIN 2479 2519 EGF-like 10.
 DOMAIN 2523 2564 LDL-receptor class A 11.
 DOMAIN 2565 2603 LDL-receptor class A 12.
 DOMAIN 2604 2642 LDL-receptor class A 13.
 DOMAIN 2643 2691 LDL-receptor class A 14.
 DOMAIN 2695 2733 LDL-receptor class A 15.
 DOMAIN 2733 2772 LDL-receptor class A 16.
 DOMAIN 2773 2815 LDL-receptor class A 17.
 DOMAIN 2817 2856 LDL-receptor class A 18.
 DOMAIN 2857 2900 LDL-receptor class A 19.
 DOMAIN 2903 2941 LDL-receptor class A 20.
 DOMAIN 2942 2982 EGF-like 11.
 DOMAIN 2983 3023 EGF-like 12; calcium-binding (Potential).
 REPEAT 3070 3114 LDL-receptor class B 26.
 REPEAT 3115 3157 LDL-receptor class B 27.
 REPEAT 3158 3201 LDL-receptor class B 28.
 REPEAT 3202 3244 LDL-receptor class B 29.
 REPEAT 3245 3285 LDL-receptor class B 30.
 DOMAIN 3291 3332 EGF-like 13.
 DOMAIN 3333 3372 LDL-receptor class A 21.
 DOMAIN 3373 3411 LDL-receptor class A 22.
 DOMAIN 3412 3451 LDL-receptor class A 23.
 DOMAIN 3452 3492 LDL-receptor class A 24.
 DOMAIN 3493 3534 LDL-receptor class A 25.
 DOMAIN 3535 3573 LDL-receptor class A 26.
 DOMAIN 3574 3612 LDL-receptor class A 27.
 DOMAIN 3612 3650 LDL-receptor class A 28.
 DOMAIN 3653 3693 LDL-receptor class A 29.
 DOMAIN 3694 3734 LDL-receptor class A 30.
 DOMAIN 3740 3779 LDL-receptor class A 31.
 DOMAIN 3782 3824 EGF-like 14.
 DOMAIN 3825 3862 EGF-like 15.
 REPEAT 3913 3955 LDL-receptor class B 31.
 REPEAT 3971 4013 LDL-receptor class B 32.
 REPEAT 4014 4057 LDL-receptor class B 33.
 REPEAT 4058 4102 LDL-receptor class B 34.
 DOMAIN 4148 4184 EGF-like 16.
 DOMAIN 4197 4233 EGF-like 17.
 DOMAIN 4233 4269 EGF-like 18.
 DOMAIN 4269 4305 EGF-like 19.
 DOMAIN 4305 4341 EGF-like 20.
 DOMAIN 4341 4376 EGF-like 21.
 DOMAIN 4374 4410 EGF-like 22.
 REGION 4446 4545 Interaction with MAFB.
 MOTIF 3941 3944 Recognition site for proteolytical
 MOTIF 4503 4508 NPXY motif.
 METAL 872 872 Calcium 1; via carbonyl oxygen (By
 METAL 875 875 Calcium 1 (By similarity).
 METAL 877 877 Calcium 1; via carbonyl oxygen (By
 METAL 879 879 Calcium 1 (By similarity).
 METAL 885 885 Calcium 1 (By similarity).
 METAL 886 886 Calcium 1 (By similarity).
 METAL 1033 1033 Calcium 2; via carbonyl oxygen (By
 METAL 1036 1036 Calcium 2 (By similarity).
 METAL 1038 1038 Calcium 2; via carbonyl oxygen (By
 METAL 1040 1040 Calcium 2 (By similarity).
 METAL 1046 1046 Calcium 2 (By similarity).
 METAL 1047 1047 Calcium 2 (By similarity).
 METAL 1081 1081 Calcium 3; via carbonyl oxygen (By
 METAL 1084 1084 Calcium 3 (By similarity).
 METAL 1086 1086 Calcium 3; via carbonyl oxygen (By
 METAL 1088 1088 Calcium 3 (By similarity).
 METAL 1094 1094 Calcium 3 (By similarity).
 METAL 1095 1095 Calcium 3 (By similarity).
 MOD_RES 4508 4508 Phosphotyrosine (By similarity).
 MOD_RES 4521 4521 Phosphoserine.
 MOD_RES 4524 4524 Phosphoserine.
 MOD_RES 4525 4525 Phosphothreonine.
 CARBOHYD 115 115 N-linked (GlcNAc...) (Potential).
 CARBOHYD 137 137 N-linked (GlcNAc...) (Potential).
 CARBOHYD 186 186 N-linked (GlcNAc...) (Potential).
 CARBOHYD 240 240 N-linked (GlcNAc...) (Potential).
 CARBOHYD 275 275 N-linked (GlcNAc...) (Potential).
 CARBOHYD 358 358 N-linked (GlcNAc...) (Potential).
 CARBOHYD 447 447 N-linked (GlcNAc...).
 CARBOHYD 730 730 N-linked (GlcNAc...).
 CARBOHYD 929 929 N-linked (GlcNAc...) (Potential).
 CARBOHYD 1051 1051 N-linked (GlcNAc...) (Potential).
 CARBOHYD 1155 1155 N-linked (GlcNAc...) (Potential).
 CARBOHYD 1156 1156 N-linked (GlcNAc...) (Potential).
 CARBOHYD 1196 1196 N-linked (GlcNAc...) (Potential).
 CARBOHYD 1219 1219 N-linked (GlcNAc...) (Potential).
 CARBOHYD 1512 1512 N-linked (GlcNAc...) (Potential).
 CARBOHYD 1559 1559 N-linked (GlcNAc...) (Potential).
 CARBOHYD 1576 1576 N-linked (GlcNAc...) (Potential).
 CARBOHYD 1617 1617 N-linked (GlcNAc...) (Potential).
 CARBOHYD 1646 1646 N-linked (GlcNAc...) (Potential).
 CARBOHYD 1724 1724 N-linked (GlcNAc...) (Potential).
 CARBOHYD 1734 1734 N-linked (GlcNAc...) (Potential).
 CARBOHYD 1764 1764 N-linked (GlcNAc...) (Potential).
 CARBOHYD 1826 1826 N-linked (GlcNAc...) (Potential).
 CARBOHYD 1934 1934 N-linked (GlcNAc...) (Potential).
 CARBOHYD 1996 1996 N-linked (GlcNAc...) (Potential).
 CARBOHYD 2049 2049 N-linked (GlcNAc...) (Potential).
 CARBOHYD 2118 2118 N-linked (GlcNAc...) (Potential).
 CARBOHYD 2128 2128 N-linked (GlcNAc...).
 CARBOHYD 2473 2473 N-linked (GlcNAc...) (Potential).
 CARBOHYD 2503 2503 N-linked (GlcNAc...) (Potential).
 CARBOHYD 2522 2522 N-linked (GlcNAc...) (Potential).
 CARBOHYD 2602 2602 N-linked (GlcNAc...) (Potential).
 CARBOHYD 2621 2621 N-linked (GlcNAc...) (Potential).
 CARBOHYD 2639 2639 N-linked (GlcNAc...) (Potential).
 CARBOHYD 2816 2816 N-linked (GlcNAc...) (Potential).
 CARBOHYD 2906 2906 N-linked (GlcNAc...) (Potential).
 CARBOHYD 3049 3049 N-linked (GlcNAc...).
 CARBOHYD 3090 3090 N-linked (GlcNAc...) (Potential).
 CARBOHYD 3265 3265 N-linked (GlcNAc...) (Potential).
 CARBOHYD 3334 3334 N-linked (GlcNAc...) (Potential).
 CARBOHYD 3489 3489 N-linked (GlcNAc...) (Potential).
 CARBOHYD 3663 3663 N-linked (GlcNAc...) (Potential).
 CARBOHYD 3789 3789 N-linked (GlcNAc...) (Potential).
 CARBOHYD 3840 3840 N-linked (GlcNAc...) (Potential).
 CARBOHYD 3954 3954 N-linked (GlcNAc...) (Potential).
 CARBOHYD 4076 4076 N-linked (GlcNAc...) (Potential).
 CARBOHYD 4126 4126 N-linked (GlcNAc...) (Potential).
 CARBOHYD 4180 4180 N-linked (GlcNAc...) (Potential).
 CARBOHYD 4279 4279 N-linked (GlcNAc...) (Potential).
 CARBOHYD 4280 4280 N-linked (GlcNAc...) (Potential).
 CARBOHYD 4365 4365 N-linked (GlcNAc...) (Potential).
 DISULFID 28 41 By similarity.
 DISULFID 35 54 By similarity.
 DISULFID 48 65 By similarity.
 DISULFID 73 86 By similarity.
 DISULFID 80 99 By similarity.
 DISULFID 93 109 By similarity.
 DISULFID 116 125 By similarity.
 DISULFID 121 134 By similarity.
 DISULFID 136 149 By similarity.
 DISULFID 155 165 By similarity.
 DISULFID 161 174 By similarity.
 DISULFID 176 189 By similarity.
 DISULFID 479 494 By similarity.
 DISULFID 490 505 By similarity.
 DISULFID 507 520 By similarity.
 DISULFID 808 819 By similarity.
 DISULFID 815 828 By similarity.
 DISULFID 830 843 By similarity.
 DISULFID 855 867 By similarity.
 DISULFID 862 880 By similarity.
 DISULFID 874 891 By similarity.
 DISULFID 896 908 By similarity.
 DISULFID 903 921 By similarity.
 DISULFID 915 932 By similarity.
 DISULFID 937 949 By similarity.
 DISULFID 944 962 By similarity.
 DISULFID 956 972 By similarity.
 DISULFID 977 990 By similarity.
 DISULFID 985 1003 By similarity.
 DISULFID 997 1012 By similarity.
 DISULFID 1016 1028 By similarity.
 DISULFID 1023 1041 By similarity.
 DISULFID 1035 1052 By similarity.
 DISULFID 1063 1076 By similarity.
 DISULFID 1070 1089 By similarity.
 DISULFID 1083 1098 By similarity.
 DISULFID 1105 1119 By similarity.
 DISULFID 1113 1132 By similarity.
 DISULFID 1126 1141 By similarity.
 DISULFID 1146 1160 By similarity.
 DISULFID 1153 1173 By similarity.
 DISULFID 1167 1183 By similarity.
 DISULFID 1186 1197 By similarity.
 DISULFID 1193 1207 By similarity.
 DISULFID 1209 1222 By similarity.
 DISULFID 1228 1238 By similarity.
 DISULFID 1234 1247 By similarity.
 DISULFID 1249 1262 By similarity.
 DISULFID 1541 1554 By similarity.
 DISULFID 1550 1564 By similarity.
 DISULFID 1566 1579 By similarity.
 DISULFID 1851 1862 By similarity.
 DISULFID 1858 1872 By similarity.
 DISULFID 1874 1887 By similarity.
 DISULFID 2160 2171 By similarity.
 DISULFID 2167 2181 By similarity.
 DISULFID 2183 2195 By similarity.
 DISULFID 2483 2494 By similarity.
 DISULFID 2490 2504 By similarity.
 DISULFID 2506 2518 By similarity.
 DISULFID 2525 2538 By similarity.
 DISULFID 2533 2551 By similarity.
 DISULFID 2545 2562 By similarity.
 DISULFID 2567 2579 By similarity.
 DISULFID 2574 2592 By similarity.
 DISULFID 2586 2601 By similarity.
 DISULFID 2606 2618 By similarity.
 DISULFID 2613 2631 By similarity.
 DISULFID 2625 2640 By similarity.
 DISULFID 2645 2667 By similarity.
 DISULFID 2661 2680 By similarity.
 DISULFID 2674 2689 By similarity.
 DISULFID 2697 2709 By similarity.
 DISULFID 2704 2722 By similarity.
 DISULFID 2716 2731 By similarity.
 DISULFID 2735 2747 By similarity.
 DISULFID 2742 2760 By similarity.
 DISULFID 2754 2770 By similarity.
 DISULFID 2775 2788 By similarity.
 DISULFID 2782 2801 By similarity.
 DISULFID 2795 2813 By similarity.
 DISULFID 2819 2831 By similarity.
 DISULFID 2826 2844 By similarity.
 DISULFID 2838 2854 By similarity.
 DISULFID 2859 2871 By similarity.
 DISULFID 2866 2885 By similarity.
 DISULFID 2879 2898 By similarity.
 DISULFID 2905 2918 By similarity.
 DISULFID 2913 2931 By similarity.
 DISULFID 2925 2940 By similarity.
 DISULFID 2945 2957 By similarity.
 DISULFID 2953 2966 By similarity.
 DISULFID 2968 2981 By similarity.
 DISULFID 2987 2997 By similarity.
 DISULFID 2993 3006 By similarity.
 DISULFID 3008 3022 By similarity.
 DISULFID 3295 3306 By similarity.
 DISULFID 3302 3316 By similarity.
 DISULFID 3318 3331 By similarity.
 DISULFID 3335 3347 By similarity.
 DISULFID 3342 3360 By similarity.
 DISULFID 3354 3370 By similarity.
 DISULFID 3375 3387 By similarity.
 DISULFID 3382 3400 By similarity.
 DISULFID 3394 3409 By similarity.
 DISULFID 3414 3427 By similarity.
 DISULFID 3421 3440 By similarity.
 DISULFID 3434 3449 By similarity.
 DISULFID 3454 3467 By similarity.
 DISULFID 3461 3480 By similarity.
 DISULFID 3474 3490 By similarity.
 DISULFID 3495 3508 By similarity.
 DISULFID 3502 3521 By similarity.
 DISULFID 3515 3532 By similarity.
 DISULFID 3537 3549 By similarity.
 DISULFID 3544 3562 By similarity.
 DISULFID 3556 3571 By similarity.
 DISULFID 3576 3588 By similarity.
 DISULFID 3583 3601 By similarity.
 DISULFID 3595 3610 By similarity.
 DISULFID 3614 3626 By similarity.
 DISULFID 3621 3639 By similarity.
 DISULFID 3633 3648 By similarity.
 DISULFID 3655 3667 By similarity.
 DISULFID 3662 3680 By similarity.
 DISULFID 3674 3691 By similarity.
 DISULFID 3696 3710 By similarity.
 DISULFID 3704 3723 By similarity.
 DISULFID 3717 3732 By similarity.
 DISULFID 3742 3755 By similarity.
 DISULFID 3750 3768 By similarity.
 DISULFID 3762 3777 By similarity.
 DISULFID 3786 3799 By similarity.
 DISULFID 3793 3808 By similarity.
 DISULFID 3810 3823 By similarity.
 DISULFID 3829 3839 By similarity.
 DISULFID 3835 3848 By similarity.
 DISULFID 3850 3861 By similarity.
 DISULFID 4152 4161 By similarity.
 DISULFID 4157 4170 By similarity.
 DISULFID 4172 4183 By similarity.
 DISULFID 4201 4211 By similarity.
 DISULFID 4205 4221 By similarity.
 DISULFID 4223 4232 By similarity.
 DISULFID 4237 4247 By similarity.
 DISULFID 4241 4257 By similarity.
 DISULFID 4259 4268 By similarity.
 DISULFID 4273 4283 By similarity.
 DISULFID 4277 4293 By similarity.
 DISULFID 4295 4304 By similarity.
 DISULFID 4309 4319 By similarity.
 DISULFID 4313 4329 By similarity.
 DISULFID 4331 4340 By similarity.
 DISULFID 4345 4353 By similarity.
 DISULFID 4348 4364 By similarity.
 DISULFID 4366 4375 By similarity.
 DISULFID 4378 4388 By similarity.
 DISULFID 4382 4398 By similarity.
 DISULFID 4400 4409 By similarity.  

Keyword

 Calcium; Cell membrane; Coated pit; Complete proteome; Cytoplasm; Developmental protein; Disulfide bond; EGF-like domain; Endocytosis; Glycoprotein; Membrane; Metal-binding; Nucleus; Phosphoprotein; Receptor; Reference proteome; Repeat; Signal; Transmembrane; Transmembrane helix. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 4545 AA 

Protein Sequence

Gene Ontology

 GO:0005905; C:coated pit; IEA:UniProtKB-SubCell.
 GO:0005887; C:integral to plasma membrane; IDA:UniProtKB.
 GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
 GO:0048471; C:perinuclear region of cytoplasm; ISO:MGI.
 GO:0005509; F:calcium ion binding; IDA:UniProtKB.
 GO:0035909; P:aorta morphogenesis; IMP:BHF-UCL.
 GO:0043277; P:apoptotic cell clearance; IMP:MGI.
 GO:0097242; P:beta-amyloid clearance; IMP:BHF-UCL.
 GO:0008203; P:cholesterol metabolic process; IMP:MGI.
 GO:2000587; P:negative regulation of platelet-derived growth factor receptor-beta signaling pathway; IMP:BHF-UCL.
 GO:0014912; P:negative regulation of smooth muscle cell migration; IMP:BHF-UCL.
 GO:0030178; P:negative regulation of Wnt receptor signaling pathway; IDA:MGI.
 GO:0010875; P:positive regulation of cholesterol efflux; IMP:BHF-UCL.
 GO:0006898; P:receptor-mediated endocytosis; IDA:MGI.
 GO:0032956; P:regulation of actin cytoskeleton organization; IMP:BHF-UCL.
 GO:0032429; P:regulation of phospholipase A2 activity; IMP:BHF-UCL. 

Interpro

 IPR011042; 6-blade_b-propeller_TolB-like.
 IPR006150; Cys_repeat_1.
 IPR000742; EG-like_dom.
 IPR001881; EGF-like_Ca-bd.
 IPR013032; EGF-like_CS.
 IPR000152; EGF-type_Asp/Asn_hydroxyl_site.
 IPR018097; EGF_Ca-bd_CS.
 IPR009030; Growth_fac_rcpt_N_dom.
 IPR023415; LDLR_class-A_CS.
 IPR000033; LDLR_classB_rpt.
 IPR002172; LDrepeatLR_classA_rpt. 

Pfam

 PF07645; EGF_CA
 PF00057; Ldl_recept_a
 PF00058; Ldl_recept_b 

SMART

 SM00181; EGF
 SM00179; EGF_CA
 SM00192; LDLa
 SM00135; LY
 SM00289; WR1 

PROSITE

 PS00010; ASX_HYDROXYL
 PS00022; EGF_1
 PS01186; EGF_2
 PS50026; EGF_3
 PS01187; EGF_CA
 PS01209; LDLRA_1
 PS50068; LDLRA_2
 PS51120; LDLRB 

PRINTS