CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-023531
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 80 kDa MCM3-associated protein 
Protein Synonyms/Alias
 Protein GANP 
Gene Name
 Mcm3ap 
Gene Synonyms/Alias
 Ganp; Map80 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
483ASAALARKKGKGLHKacetylation[1]
484SAALARKKGKGLHKDacetylation[1]
774INNENMTKCLQSLKEubiquitination[2]
Reference
 [1] Label-free quantitative proteomics of the lysine acetylome in mitochondria identifies substrates of SIRT3 in metabolic pathways.
 Rardin MJ, Newman JC, Held JM, Cusack MP, Sorensen DJ, Li B, Schilling B, Mooney SD, Kahn CR, Verdin E, Gibson BW.
 Proc Natl Acad Sci U S A. 2013 Apr 16;110(16):6601-6. [PMID: 23576753]
 [2] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
 May be involved in the nuclear localization pathway of MCM3 (By similarity). 
Sequence Annotation
 MOD_RES 531 531 Phosphoserine (By similarity).  
Keyword
 Complete proteome; Cytoplasm; Nucleus; Phosphoprotein; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1971 AA 
Protein Sequence
MHPVNPFGGQ QPSAFAVSSS TTGTYQTKSP FRFGQPSLFG QNSTPSKSLA FSQVPSFATP 60
SGGSHSSSLP AFGLTQTSSV GLFSSLESTP SFAATSSSSV PGNTAFSFKS TSSVGVFPSG 120
ATFGPETGEV AGSGFRKTEF KFKPLENAVF KPIPGPESEP EKTQSQISSG FFTFSHPVGS 180
GSGGLTPFSF PQVTNSSVTS SSFIFSKPVT SNTPAFASPL SNQNVEEEKR VSTSAFGSSN 240
SSFSTFPTAS PGSLGEPFPA NKPSLRQGCE EAISQVEPLP TLMKGLKRKE DQDRSPRRHC 300
HEAAEDPDPL SRGDHPPDKR PVRLNRPRGG TLFGRTIQEV FKSNKEAGRL GSKESKESGF 360
AEPGESDHAA VPGGSQSTMV PSRLPAVTKE EEESRDEKED SLRGKSVRQS KRREEWIYSL 420
GGVSSLELTA IQCKNIPDYL NDRAILEKHF SKIAKVQRVF TRRSKKLAVI HFFDHASAAL 480
ARKKGKGLHK DVVIFWHKKK ISPSKKLFPL KEKLGESEAS QGIEDSPFQH SPLSKPIVRP 540
AAGSLLSKSS PVKKPSLLKM HQFEADPFDS GSEGSEGLGS CVSSLSTLIG TVADTSEEKY 600
RLLDQRDRIM RQARVKRTDL DKARAFVGTC PDMCPEKERY LRETRSQLSV FEVVPGTDQV 660
DHAAAVKEYS RSSADQEEPL PHELRPSAVL SRTMDYLVTQ IMDQKEGSLR DWYDFVWNRT 720
RGIRKDITQQ HLCDPLTVSL IEKCTRFHIH CAHFMCEEPM SSFDAKINNE NMTKCLQSLK 780
EMYQDLRNKG VFCASEAEFQ GYNVLLNLNK GDILREVQQF HPDVRNSPEV NFAVQAFAAL 840
NSNNFVRFFK LVQSASYLNA CLLHCYFNQI RKDALRALNV AYTVSTQRST VFPLDGVVRM 900
LLFRDSEEAT NFLNYHGLTV ADGCVELNRS AFLEPEGLCK ARKSVFIGRK LTVSVGEVVN 960
GGPLPPVPRH TPVCSFNSQN KYVGESLATE LPISTQRAGG DPAGGGRGED CEAEVDVPTL 1020
AVLPQPPPAS SATPALHVQP LAPAAAPSLL QASTQPEVLL PKPAPVYSDS DLVQVVDELI 1080
QEALQVDCEE VSSAGAAYVA AALGVSNAAV EDLITAATTG ILRHVAAEEV SMERQRLEEE 1140
KQRAEEERLK QERELMLTQL SEGLAAELTE LTVTECVWET CSQELQSAVE IDQKVRVARC 1200
CEAVCAHLVD LFLAEEIFQT AKETLQELQC FCKYLQRWRE AVAARKKFRR QMRAFPAAPC 1260
CVDVNDRLQA LVPSAECPIT EENLAKGLLD LGHAGKVGVS CTRLRRLRNK TAHQIKVQHF 1320
HQQLLRNAAW APLDLPSIVS EHLPMKQKRR FWKLVLVLPD VEEQTPESPG RILENWLKVK 1380
FTGDDSMVGD IGDNAGDIQT LSVFNTLSSK GDQTVSVNVC IKVAHGTLSD SALDAVETQK 1440
DLLGTSGLML LLPPKVKSEE VAEEELSWLS ALLQLKQLLQ AKPFQPALPL VVLVPSSRGD 1500
SAGRAVEDGL MLQDLVSAKL ISDYIVVEIP DSVNDLQGTV KVSGAVQWLI SRCPQALDLC 1560
CQTLVQYVED GISREFSRRF FHDRRERRLA SLPSQEPSTI IELFNSVLQF LASVVSSEQL 1620
CDISWPVMEF AEVGGSQLLP HLHWNSPEHL AWLKQAVLGF QLPQMDLPPP GAPWLPVCSM 1680
VIQYTSQIPS SSQTQPVLQS QVENLLCRTY QKWKNKSLSP GQELGPSVAE IPWDDIITLC 1740
INHKLRDWTP PRLPVTLEAL SEDGQICVYF FKNLLRKYHV PLSWEQARMQ TQRELQLSHG 1800
RSGMRSIHPP TSTFPTPLLH VHQKGKKKEE SGREGSLSTE DLLRGASAEE LLAQSLSSSL 1860
LEEKEENKRF EDQLQQWLSQ DSQAFTESTR LPLYLPQTLV SFPDSIKTQT MVKTSTSPQN 1920
SGTGKQLRFS EASGSSLTEK LKLLERLIQS SRAEEAASEL HLSALLEMVD M 1971 
Gene Ontology
 GO:0005737; C:cytoplasm; IDA:MGI.
 GO:0005829; C:cytosol; IEA:Compara.
 GO:0005634; C:nucleus; IDA:MGI. 
Interpro
 IPR005062; SAC3/GANP/Nin1/mts3/eIF-3-p25. 
Pfam
 PF03399; SAC3_GANP 
SMART
  
PROSITE
  
PRINTS