CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-002950
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Integration host factor subunit beta 
Protein Synonyms/Alias
 IHF-beta 
Gene Name
 ihfB 
Gene Synonyms/Alias
 himD; hip; b0912; JW0895 
Created Date
 July 27, 2013 
Organism
 Escherichia coli (strain K12) 
NCBI Taxa ID
 83333 
Lysine Modification
Position
Peptide
Type
References
3*****MTKSELIERLacetylation[1]
20QQSHIPAKTVEDAVKacetylation[2]
27KTVEDAVKEMLEHMAacetylation[2]
65PRTGRNPKTGDKVELacetylation[2]
69RNPKTGDKVELEGKYacetylation[2]
75DKVELEGKYVPHFKPacetylation[2]
81GKYVPHFKPGKELRDacetylation[1, 2]
84VPHFKPGKELRDRANacetylation[2]
Reference
 [1] Comprehensive profiling of protein lysine acetylation in Escherichia coli.
 Zhang K, Zheng S, Yang JS, Chen Y, Cheng Z.
 J Proteome Res. 2013 Feb 1;12(2):844-51. [PMID: 23294111]
 [2] Acetyl-Phosphate Is a Critical Determinant of Lysine Acetylation in E. coli.
 Weinert BT, Iesmantavicius V, Wagner SA, Schölz C, Gummesson B, Beli P, Nyström T, Choudhary C.
 Mol Cell. 2013 Jul 25;51(2):265-72. [PMID: 23830618
Functional Description
 One of the 2 subunits of integration host factor (IHF), a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control. 
Sequence Annotation
  
Keyword
 3D-structure; Complete proteome; Conjugation; Cytoplasm; Direct protein sequencing; DNA recombination; DNA-binding; Reference proteome; Transcription; Transcription regulation; Translation regulation. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 94 AA 
Protein Sequence
MTKSELIERL ATQQSHIPAK TVEDAVKEML EHMASTLAQG ERIEIRGFGS FSLHYRAPRT 60
GRNPKTGDKV ELEGKYVPHF KPGKELRDRA NIYG 94 
Gene Ontology
 GO:0005694; C:chromosome; IEA:InterPro.
 GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
 GO:0003677; F:DNA binding; IEA:HAMAP.
 GO:0000746; P:conjugation; IEA:UniProtKB-KW.
 GO:0006310; P:DNA recombination; IEA:HAMAP.
 GO:0006355; P:regulation of transcription, DNA-dependent; IEA:HAMAP.
 GO:0006417; P:regulation of translation; IEA:HAMAP.
 GO:0006351; P:transcription, DNA-dependent; IDA:EcoCyc. 
Interpro
 IPR023630; DNA-bd_HU/IHF.
 IPR000119; Hist_DNA-bd_bac.
 IPR020816; Histone-like_DNA-bd_CS.
 IPR010992; IHF-like_DNA-bd_dom.
 IPR005685; IHF_beta. 
Pfam
 PF00216; Bac_DNA_binding 
SMART
 SM00411; BHL 
PROSITE
 PS00045; HISTONE_LIKE 
PRINTS
 PR01727; DNABINDINGHU.