CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-044387
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Dipeptidyl peptidase 8 
Protein Synonyms/Alias
  
Gene Name
 DPP8 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
388AGWTPEGKYAWSILLubiquitination[1, 2, 3]
Reference
 [1] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473]
 [2] Global identification of modular cullin-RING ligase substrates.
 Emanuele MJ, Elia AE, Xu Q, Thoma CR, Izhar L, Leng Y, Guo A, Chen YN, Rush J, Hsu PW, Yen HC, Elledge SJ.
 Cell. 2011 Oct 14;147(2):459-74. [PMID: 21963094]
 [3] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 729 AA 
Protein Sequence
MWKRSEQMKI KSGKCNMAAA METEQLGVEI FETADCEENI ESQDRPKLEP FYVERYSWSQ 60
LKKLLADTRK YHGYMMAKAP HDFMFVKRND PDGPHSDRIY YLAMSGENRE NTLFYSEIPK 120
TINRAAVLML SWKPLLDLFQ ATLDYGMYSR EEELLRERKR IGTVGIASYD YHQGSGTFLF 180
QAGSGIYHVK DGGPQGFTQQ PLRPNLVETS CPNIRMDPKL CPADPDWIAF IHSNDIWISN 240
IVTREERRLT YVHNELANME EDARSAGVAT FVLQEEFDRY SGYWWCPKAE TTPSGGKILR 300
ILYEENDESE VEIIHVTSPM LETRRADSFR YPKTGTANPK VTFKMSEIMI DAEGRIIDVI 360
DKELIQPFEI LFEGVEYIAR AGWTPEGKYA WSILLDRSQT RLQIVLISPE LFIPVEDDVM 420
ERQRLIESVP DSVTPLIIYE ETTDIWINIH DIFHVFPQSH EEEIEFIFAS ECKTGFRHLY 480
KITSILKESK YKRSSGGLPA PSDFKCPIKE EIAITSGEWE VLGRHGSNIQ VDEVRRLVYF 540
EGTKDSPLEH HLYVVSYVNP GEVTRLTDRG YSHSCCISQH CDFFISKYSN QKNPHCVSLY 600
KLSSPEDDPT CKTKEFWATI LDSAGPLPDY TPPEIFSFES TTGFTLYGML YKPHDLQPGK 660
KYPTVLFIYG GPQVQLVNNR FKGVKYFRLN TLASLGYVVV VIDNRGSCHR GLKFEGAFKY 720
KMEALNATF 729 
Gene Ontology
 GO:0016020; C:membrane; IEA:InterPro.
 GO:0006508; P:proteolysis; IEA:InterPro. 
Interpro
 IPR002469; Peptidase_S9B. 
Pfam
 PF00930; DPPIV_N 
SMART
  
PROSITE
  
PRINTS