CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-024890
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Leucine rich repeat containing 54, isoform CRA_a 
Protein Synonyms/Alias
 Tsku protein 
Gene Name
 Tsku 
Gene Synonyms/Alias
 Lrrc54; mCG_51625 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
267LDLSGNPKLKWAGAEubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
  
Keyword
 Leucine-rich repeat; Repeat. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 354 AA 
Protein Sequence
MLCSLFLLLL AVGRVQTTRP CFPGCQCEEE TFGLFDSFSL IRVDCSSLGP HIVPVPIPLD 60
TAHLDLSSNR LETVNESVLA GPGYTTLAGL DLSYNLLTSI MPSAFSRLRY LESLDLSHNG 120
LAALPAEIFT SSPLSDINLS HNRLREVSIS AFTTHSQGRA LHVDLSHNLI HRLLPHPARA 180
SLPAPTIQSL NLSWNRFRAV PDLRDLPLRY LSLDGNPLAT INPDAFMGLA GLTHLSLASL 240
QGILHLPPHG FRELPGLQVL DLSGNPKLKW AGAEVFSGLG LLQELDLSGS SLVPLPEMLL 300
HHLPALQSVS VGQDVQCRRL VREGAYHRQP GSSPKVVLHC GDTQESAARG PDIL 354 
Gene Ontology
 GO:0005615; C:extracellular space; IDA:MGI.
 GO:0021960; P:anterior commissure morphogenesis; IMP:MGI.
 GO:0061073; P:ciliary body morphogenesis; IMP:MGI.
 GO:0021540; P:corpus callosum morphogenesis; IMP:MGI.
 GO:0021670; P:lateral ventricle development; IMP:MGI.
 GO:0030178; P:negative regulation of Wnt receptor signaling pathway; IDA:MGI.
 GO:0010468; P:regulation of gene expression; IMP:MGI. 
Interpro
 IPR001611; Leu-rich_rpt.
 IPR003591; Leu-rich_rpt_typical-subtyp.
 IPR000372; LRR-contain_N. 
Pfam
 PF00560; LRR_1 
SMART
 SM00369; LRR_TYP
 SM00013; LRRNT 
PROSITE
 PS51450; LRR 
PRINTS