CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-020883
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Copper homeostasis protein cutC homolog 
Protein Synonyms/Alias
  
Gene Name
 Cutc 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
206PGGGITDKNLQRILEubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023
Functional Description
 May play a role in copper homeostasis. Can bind one Cu(1+) per subunit (By similarity). 
Sequence Annotation
  
Keyword
 Complete proteome; Copper; Cytoplasm; Metal-binding; Nucleus; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 272 AA 
Protein Sequence
MKKGASCERK QAWISSGKAG AGNGFLMEVC VDSVESAVNA ERGGAGRIEL CSGLLEGGTT 60
PSMGVLQVVK QSVQIPVFVM IRPRGGDFLY SDREVEVMKA DIRLAKLYGA DGLVFGALTE 120
DGHIDKELCL SLVALCRPLP VTFHRAFDMV HDPMAALETL LTLGFERVLT SGCDSSALEG 180
LPLIKQLIDQ AKGRIVVMPG GGITDKNLQR ILEGSGATEF HCSARSSRDS GMKFRNSSVA 240
MGASLAHSEY SLKVTDVTKV RTLNAIAKDV LV 272 
Gene Ontology
 GO:0016235; C:aggresome; IEA:Compara.
 GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
 GO:0005730; C:nucleolus; IEA:Compara.
 GO:0005507; F:copper ion binding; ISS:UniProtKB.
 GO:0055070; P:copper ion homeostasis; IEA:InterPro.
 GO:0051262; P:protein tetramerization; IEA:Compara. 
Interpro
 IPR005627; Cu_homeostasis_CutC.
 IPR023648; Cu_homeostasis_CutC_dom. 
Pfam
 PF03932; CutC 
SMART
  
PROSITE
  
PRINTS