CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-011328
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Heat shock protein SSQ1, mitochondrial 
Protein Synonyms/Alias
 Stress-seventy subfamily Q protein 1; mtHSP70 homolog 
Gene Name
 SSQ1 
Gene Synonyms/Alias
 SSC2; YLR369W 
Created Date
 July 27, 2013 
Organism
 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 
NCBI Taxa ID
 559292 
Lysine Modification
Position
Peptide
Type
References
607SNIVEDIKALRQAIKacetylation[1]
Reference
 [1] Proteome-wide analysis of lysine acetylation suggests its broad regulatory scope in Saccharomyces cerevisiae.
 Henriksen P, Wagner SA, Weinert BT, Sharma S, Bacinskaja G, Rehman M, Juffer AH, Walther TC, Lisby M, Choudhary C.
 Mol Cell Proteomics. 2012 Nov;11(11):1510-22. [PMID: 22865919] 
Functional Description
 Has a role in mitochondrial iron homeostasis. Appears to be involved in the processing of the intermediate form of the frataxin homolog YFH1. Required for the assembly of iron-sulfur (Fe/S) clusters in mitochondria. 
Sequence Annotation
  
Keyword
 ATP-binding; Chaperone; Complete proteome; Mitochondrion; Nucleotide-binding; Reference proteome; Stress response; Transit peptide. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 657 AA 
Protein Sequence
MLKSGRLNFL KLNINSRLLY STNPQLTKKV IGIDLGTTNS AVAYIRDSND KKSATIIEND 60
EGQRTTPSIV AFDVKSSPQN KDQMKTLVGM AAKRQNAINS ENTFFATKRL IGRAFNDKEV 120
QRDMAVMPYK IVKCESNGQA YLSTSNGLIQ SPSQIASILL KYLKQTSEEY LGEKVNLAVI 180
TVPAYFNDSQ RQATKDAGKL AGLNVLRVIN EPTAAALSFG IDDKRNNGLI AVYDLGGGTF 240
DISILDIEDG VFEVRATNGD THLGGEDFDN VIVNYIIDTF IHENPEITRE EITKNRETMQ 300
RLKDVSERAK IDLSHVKKTF IELPFVYKSK HLRVPMTEEE LDNMTLSLIN RTIPPVKQAL 360
KDADIEPEDI DEVILVGGMT RMPKIRSVVK DLFGKSPNSS VNPDETVALG AAIQGGILSG 420
EIKNVLLLDV TPLTLGIETF GGAFSPLIPR NTTVPVKKTE IFSTGVDGQA GVDIKVFQGE 480
RGLVRNNKLI GDLKLTGITP LPKGIPQIYV TFDIDADGII NVSAAEKSSG KQQSITVIPN 540
SGLSEEEIAK LIEEANANRA QDNLIRQRLE LISKADIMIS DTENLFKRYE KLISSEKEYS 600
NIVEDIKALR QAIKNFKANE NDMSIDVNGI KKATDALQGR ALKLFQSATK NQQNQGK 657 
Gene Ontology
 GO:0005759; C:mitochondrial matrix; IDA:SGD.
 GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
 GO:0051082; F:unfolded protein binding; ISS:SGD.
 GO:0006880; P:intracellular sequestering of iron ion; IMP:SGD.
 GO:0016226; P:iron-sulfur cluster assembly; IMP:SGD.
 GO:0051604; P:protein maturation; IMP:SGD.
 GO:0006950; P:response to stress; IEA:UniProtKB-KW. 
Interpro
 IPR018181; Heat_shock_70_CS.
 IPR013126; Hsp_70_fam. 
Pfam
 PF00012; HSP70 
SMART
  
PROSITE
 PS00297; HSP70_1
 PS00329; HSP70_2
 PS01036; HSP70_3 
PRINTS
 PR00301; HEATSHOCK70.