UniProt Accession

 PGRC2_MOUSE; Q80UU9 

Genbank Protein ID

 AC100511; BC044759 

Genbank Nucleotide ID

 AAH44759.1 

Protein Name

 Membrane-associated progesterone receptor component 2 

Protein Synonyms/Alias

  

Gene Name

 Pgrmc2 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Mus musculus (Mouse) 

NCBI Taxa ID

 10090 

Lysine Modification

Position	Peptide	Type	References
120	ILLAVNGKVFDVTKG	ubiquitination	[1]
126	GKVFDVTKGSKFYGP	ubiquitination	[1]
129	FDVTKGSKFYGPAGP	ubiquitination	[1]
185	REWEMQFKEKYDYVG	ubiquitination	[1]
187	WEMQFKEKYDYVGRL	acetylation	[2]
187	WEMQFKEKYDYVGRL	ubiquitination	[1]

Reference

 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023]
 [2] Calorie restriction and SIRT3 trigger global reprogramming of the mitochondrial protein acetylome.
 Hebert AS, Dittenhafer-Reed KE, Yu W, Bailey DJ, Selen ES, Boersma MD, Carson JJ, Tonelli M, Balloon AJ, Higbee AJ, Westphall MS, Pagliarini DJ, Prolla TA, Assadi-Porter F, Roy S, Denu JM, Coon JJ.
 Mol Cell. 2013 Jan 10;49(1):186-99. [PMID: 23201123] 

Functional Description

 Receptor for steroids (Potential). 

Sequence Annotation

 DOMAIN 96 195 Cytochrome b5 heme-binding.
 MOD_RES 84 84 Phosphoserine (By similarity).
 MOD_RES 202 202 Phosphoserine.
 MOD_RES 204 204 Phosphotyrosine (By similarity).
 MOD_RES 205 205 Phosphothreonine.  

Keyword

 Complete proteome; Lipid-binding; Membrane; Phosphoprotein; Receptor; Reference proteome; Steroid-binding; Transmembrane; Transmembrane helix. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 217 AA 

Protein Sequence

Gene Ontology

 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0020037; F:heme binding; IEA:InterPro.
 GO:0005496; F:steroid binding; IEA:UniProtKB-KW. 

Interpro

 IPR001199; Cyt_B5-like_heme/steroid-bd. 

Pfam

 PF00173; Cyt-b5 

SMART

  

PROSITE

 PS00191; CYTOCHROME_B5_1
 PS50255; CYTOCHROME_B5_2 

PRINTS