| Tag | Content |
|---|
| CPLM ID | CPLM-009297 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Proliferating cell nuclear antigen |
Protein Synonyms/Alias | PCNA; Cyclin |
Gene Name | PCNA |
Gene Synonyms/Alias | PF13_0328 |
Created Date | July 27, 2013 |
Organism | Plasmodium falciparum (isolate 3D7) |
NCBI Taxa ID | 36329 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 259 | TLKIGFVKFFLAPKM | acetylation | [1] |
|
Reference | [1] Extensive lysine acetylation occurs in evolutionarily conserved metabolic pathways and parasite-specific functions during Plasmodium falciparum intraerythrocytic development. Miao J, Lawrence M, Jeffers V, Zhao F, Parker D, Ge Y, Sullivan WJ Jr, Cui L. Mol Microbiol. 2013 Aug;89(4):660-75. [ PMID: 23796209] |
Functional Description | This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand (By similarity). |
Sequence Annotation | DNA_BIND 61 80 Potential. |
Keyword | Complete proteome; DNA replication; DNA-binding; Nucleus; Reference proteome. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 274 AA |
Protein Sequence | MLEAKLNNAS ILKKLFECIK DLVNDANVDA DESGLKLQAL DGNHVSLVSL HLLDSGFSHY 60
RCDRERVLGV NIASLNKVFK LCGANESVVI SSKDDEDNLN FVFENNKEDK VTNFSLKLMS 120
IELDSLNIPD CEEGFDAEVE LSSKELTNIF RNLSEFSDTV FIEIDSNCIK FTTKGIVGDA 180
EVALKPRDST SEDDIGVTIK SKKKIKQSFA IKYLNLFSKS NILADVVVLG LSDSRPIEFK 240
YEIKDTSPDS DTLKIGFVKF FLAPKMDDDM DNKD 274 |
Gene Ontology | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. GO:0043626; C:PCNA complex; IEA:InterPro. GO:0003677; F:DNA binding; IEA:UniProtKB-KW. GO:0030337; F:DNA polymerase processivity factor activity; IEA:InterPro. GO:0006260; P:DNA replication; IEA:UniProtKB-KW. GO:0006275; P:regulation of DNA replication; IEA:InterPro. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |