CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-042378
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 NADPH--cytochrome P450 reductase 
Protein Synonyms/Alias
  
Gene Name
 POR 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
541TKAGRINKGVATNWLubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 725 AA 
Protein Sequence
XTDMILFSLI VGLLTYWFLF RKKKEEVPEF TKIQTLTSSV RESSFVEKMK KTGRNIIVFY 60
GSQTGTAEEF ANRLSKDAHR YGMRGMSADP EEYDLADLSS LPEIDNALVV FCMATYGEGD 120
PTDNAQDFYD WLQETDVDLS GVKFAVSHPE TAMGSRWPAV PPWGLQIHVS ERQPSRPPPC 180
PQQPGQATCE TLSSAPDPST TRMSPPCPQP QSAPGGIGCW RLKVFGLGNK TYEHFNAMGK 240
YVDKRLEQLG AQRIFELGLG DDDGNLEEDF ITWREQFWPA VCEHFGVEAT GEESSIRQYE 300
LVVHTDIDAA KVYMGEMGRL KSYENQKPPF DAKNPFLAAV TTNRKLNQGT ERHLMHLELD 360
ISDSKIRYES GDHVAVYPAN DSALVNQLGK ILGADLDVVM SLNNLDEESN KKHPFPCPTS 420
YRTALTYYLD ITNPPRTNVL YELAQYASEP SEQELLRKMA SSSGEGKELY LSWVVEARRH 480
ILAILQDCPS LRPPIDHLCE LLPRLQARYY SIASSSKVHP NSVHICAVVV EYETKAGRIN 540
KGVATNWLRA KEPAGENGGR ALVPMFVRKS QFRLPFKATT PVIMVGPGTG VAPFIGFIQE 600
RAWLRQQGKE VGETLLYYGC RRSDEDYLYR EELAQFHRDG ALTQLNVAFS REQSHKVYVQ 660
HLLKQDREHL WKLIEGGAHI YVCGTPSSCP GMHGTWPGMC RTPSTTSWLS SGPWSTRRRW 720
TTSRN 725 
Gene Ontology
 GO:0005829; C:cytosol; IBA:RefGenome.
 GO:0010181; F:FMN binding; IEA:InterPro.
 GO:0005506; F:iron ion binding; IEA:InterPro.
 GO:0003958; F:NADPH-hemoprotein reductase activity; IBA:RefGenome.
 GO:0016709; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen; IBA:RefGenome. 
Interpro
 IPR003097; FAD-binding_1.
 IPR017927; Fd_Rdtase_FAD-bd.
 IPR001094; Flavdoxin.
 IPR008254; Flavodoxin/NO_synth.
 IPR001709; Flavoprot_Pyr_Nucl_cyt_Rdtase.
 IPR023173; NADPH_Cyt_P450_Rdtase_dom3.
 IPR001433; OxRdtase_FAD/NAD-bd.
 IPR023208; P450R.
 IPR017938; Riboflavin_synthase-like_b-brl. 
Pfam
 PF00667; FAD_binding_1
 PF00258; Flavodoxin_1
 PF00175; NAD_binding_1 
SMART
  
PROSITE
 PS51384; FAD_FR
 PS50902; FLAVODOXIN_LIKE 
PRINTS
 PR00369; FLAVODOXIN.
 PR00371; FPNCR.