| Tag | Content |
|---|
| CPLM ID | CPLM-016566 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Alkylglycerol monooxygenase |
Protein Synonyms/Alias | Transmembrane protein 195 |
Gene Name | Agmo |
Gene Synonyms/Alias | Tmem195 |
Created Date | July 27, 2013 |
Organism | Mus musculus (Mouse) |
NCBI Taxa ID | 10090 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 308 | GPGWGPGKPRLGLSE | ubiquitination | [1] |
|
Reference | [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues. Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C. Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [ PMID: 22790023] |
Functional Description | Glyceryl-ether monooxygenase that cleaves the O-alkyl bond of ether lipids. Ether lipids are essential components of brain membranes (By similarity). |
Sequence Annotation | MOTIF 132 136 Histidine box-1.
MOTIF 145 149 Histidine box-2.
MOTIF 221 225 Histidine box-3. |
Keyword | Alternative splicing; Complete proteome; Endoplasmic reticulum; Iron; Membrane; Oxidoreductase; Reference proteome; Transmembrane; Transmembrane helix. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 447 AA |
Protein Sequence | MRSPGAQDNV SVSQGMRAMF YMMEPSETAF QTVEEVPDYV KKATPFFIFL ILLELVISWI 60
LKGKPSGRLD DALTSISAGV VSRLPSLFFR SLEVTSYIYI WENYRLLELP WDSTWTWYFT 120
FLGVDFGYYW FHRMAHEINI FWAAHQAHHS SEDYNLSTAL RQSVLQQYSS WVFYCPLALF 180
IPPSVFAVHI QFNLLYQFWI HTEIIRTLGP LEVILNTPSH HRVHHGRNRY CIDKNYAGTL 240
IIWDRIFGTF EAENEQVIYG LTHPIGTFEP FNVQFHHLLY IWTTFWTTPG FCHKFSVLFK 300
GPGWGPGKPR LGLSEEIPEV TGQEVPFSSS ASQLLKIYTV LQFAVMLAFY EETFANTAVL 360
SQVTLLLRIF FFILTLTSIG FLLDQRSKAA TMETFRCLLF LTLHRFGHLK PLIPSLSFAF 420
EIFFSVCIAF WGVRSITQLT SGSWKKP 447 |
Gene Ontology | GO:0005783; C:endoplasmic reticulum; ISS:UniProtKB. GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell. GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. GO:0050479; F:glyceryl-ether monooxygenase activity; ISS:UniProtKB. GO:0005506; F:iron ion binding; ISS:UniProtKB. GO:0046485; P:ether lipid metabolic process; ISS:UniProtKB. GO:0006633; P:fatty acid biosynthetic process; IEA:InterPro. GO:0006643; P:membrane lipid metabolic process; ISS:UniProtKB. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |